[HTML][HTML] Symposium review: One-carbon metabolism and methyl donor nutrition in the dairy cow

JW McFadden, CL Girard, S Tao, Z Zhou… - Journal of dairy …, 2020 - Elsevier
The present review focuses on methyl donor metabolism and nutrition in the periparturient
and lactating dairy cow. Methyl donors are involved in one-carbon metabolism, which …

Multifaceted role of one-carbon metabolism on immunometabolic control and growth during pregnancy, lactation and the neonatal period in dairy cattle

DN Coleman, AS Alharthi, Y Liang, MG Lopes… - Journal of animal …, 2021 - Springer
Dairy cattle undergo dramatic metabolic, endocrine, physiologic and immune changes
during the peripartal period largely due to combined increases in energy requirements for …

Amino acids and the regulation of oxidative stress and immune function in dairy cattle

DN Coleman, V Lopreiato, A Alharthi… - Journal of Animal …, 2020 - academic.oup.com
The periparturient period is one of the most challenging periods in dairy cows and
encompasses the 3 wk prior to and 3 wk after parturition. The nutrient requirements of dairy …

Overview of the effect of rumen-protected limiting amino acids (methionine and lysine) and choline on the immunity, antioxidative, and inflammatory status of …

MZ Khan, S Liu, Y Ma, M Ma, Q Ullah, IM Khan… - Frontiers in …, 2023 - frontiersin.org
Overproduction of reactive oxygen species (ROS) is a well-known phenomenon
experienced by ruminants, especially during the transition from late gestation to successful …

Methionine promotes milk protein and fat synthesis and cell proliferation via the SNAT2-PI3K signaling pathway in bovine mammary epithelial cells

H Qi, C Meng, X Jin, X Li, P Li… - Journal of agricultural and …, 2018 - ACS Publications
Methionine (Met) plays a critical regulatory role in milk production, however, the molecular
mechanism of action of Met is largely unknown. This study therefore aimed to investigate the …

[HTML][HTML] Effects of feeding rumen-protected methionine pre-and postpartum in multiparous Holstein cows: Lactation performance and plasma amino acid …

MZ Toledo, ML Stangaferro, RS Gennari… - Journal of Dairy …, 2021 - Elsevier
Objectives were to evaluate the effect of feeding rumen-protected methionine (RPM) in pre-
and postpartum total mix ration (TMR) on lactation performance and plasma AA …

Lysine enhances the stimulation of fatty acids on milk fat synthesis via the GPRC6A-PI3K-FABP5 signaling in bovine mammary epithelial cells

X Li, P Li, L Wang, M Zhang, X Gao - Journal of agricultural and …, 2019 - ACS Publications
Amino acids can enhance milk fat synthesis in bovine mammary epithelial cells (BMECs),
but the molecular mechanism is not well-known. In this study, we explored the regulatory …

Retromer and TBC1D5 maintain late endosomal RAB7 domains to enable amino acid–induced mTORC1 signaling

A Kvainickas, H Nägele, W Qi, L Dokládal… - Journal of Cell …, 2019 - rupress.org
Retromer is an evolutionarily conserved multiprotein complex that orchestrates the endocytic
recycling of integral membrane proteins. Here, we demonstrate that retromer is also required …

[HTML][HTML] Enhanced supply of methionine or arginine alters mechanistic target of rapamycin signaling proteins, messenger RNA, and microRNA abundance in heat …

AAK Salama, M Duque, L Wang, K Shahzad… - Journal of dairy …, 2019 - Elsevier
Heat stress (HS) causes reductions in milk production, but it is unclear whether this effect is
due to reduced number or functional capacity (or both) of mammary cells. Methionine …

[HTML][HTML] Methionine and arginine supplementation alter inflammatory and oxidative stress responses during lipopolysaccharide challenge in bovine mammary …

H Dai, DN Coleman, L Hu, I Martinez-Cortés… - Journal of Dairy …, 2020 - Elsevier
Mastitis, inflammation of the udder, is one of the most common diseases hampering milk
yield of dairy cows. Methionine (Met) and arginine (Arg) are key nutrients with potential to …