The functioning of DNA in the cell nucleus is ensured by a multitude of proteins, whose
interactions with DNA as well as with other proteins lead to the formation of a complicated …

HMGB1 that belongs to the High Mobility Group-box superfamily, is a nonhistone chromatin
associated transcription factor. It is present in the nucleus of eukaryotes and can be actively …

Astrocytes are intimately linked with brain blood vessels, an essential relationship for
neuronal function. However, astroglial factors driving these physical and functional …

Alzheimer's disease (AD) is the most common form of neurodegenerative disorders
worldwide. Its pathologic features include massive neuroinflammation with abnormal …

Background Binge ethanol exposure during adolescence reduces hippocampal
neurogenesis, a reduction which persists throughout adulthood despite abstinence. This …

Background The dentate gyrus exhibits life-long neurogenesis of granule-cell neurons,
supporting hippocampal dependent learning and memory. Both temporal lobe epilepsy …

The dorsal and ventral human telencephalons contain different neuronal subtypes, including
glutamatergic, GABAergic, and cholinergic neurons, and how these neurons are generated …

We previously showed that both high-mobility group box-1 (HMGB1) and natural killer (NK)
cells contribute to respiratory syncytial virus (RSV)-induced persistent airway inflammation …

Radiation therapy represents one of the primary treatment modalities for primary and
metastatic brain tumors. Although recent advances in radiation techniques, that allow the …

Parkinson's disease (PD) is one of the most common degenerative diseases of the human
nervous system and has a wide range of serious impacts on human health and quality of life …