α-Amylase: an enzyme specificity found in various families of glycoside hydrolases

Š Janeček, B Svensson, EA MacGregor - Cellular and molecular life …, 2014 - Springer
Abstract α-Amylase (EC 3.2. 1.1) represents the best known amylolytic enzyme. It catalyzes
the hydrolysis of α-1, 4-glucosidic bonds in starch and related α-glucans. In general, the α …

The Sus operon: a model system for starch uptake by the human gut Bacteroidetes

MH Foley, DW Cockburn, NM Koropatkin - Cellular and Molecular Life …, 2016 - Springer
Resident bacteria in the densely populated human intestinal tract must efficiently compete
for carbohydrate nutrition. The Bacteroidetes, a dominant bacterial phylum in the …

[HTML][HTML] Bacterial amylases enable glycogen degradation by the vaginal microbiome

DJ Jenkins, BM Woolston, MI Hood-Pishchany… - Nature …, 2023 - nature.com
The human vaginal microbiota is frequently dominated by lactobacilli and transition to a
more diverse community of anaerobic microbes is associated with health risks. Glycogen …

Polysaccharide utilization loci and nutritional specialization in a dominant group of butyrate-producing human colonic Firmicutes

P O. Sheridan, JC Martin, TD Lawley… - Microbial …, 2016 - microbiologyresearch.org
Firmicutes and Bacteroidetes are the predominant bacterial phyla colonizing the healthy
human large intestine. Whilst both ferment dietary fibre, genes responsible for this important …

Starch digestion by gut bacteria: crowdsourcing for carbs

FM Cerqueira, AL Photenhauer, RM Pollet… - Trends in …, 2020 - cell.com
Starch is a polymer of glucose and is one of the most abundant carbohydrates in a Western
diet. Resistant starch escapes digestion by host small intestinal glucoamylases and transits …

Starch-binding domains as CBM families–history, occurrence, structure, function and evolution

Š Janeček, F Mareček, EA MacGregor… - Biotechnology Advances, 2019 - Elsevier
The term “starch-binding domain”(SBD) has been applied to a domain within an amylolytic
enzyme that gave the enzyme the ability to bind onto raw, ie thermally untreated, granular …

Unique Organization of Extracellular Amylases into Amylosomes in the Resistant Starch-Utilizing Human Colonic Firmicutes Bacterium Ruminococcus bromii

X Ze, Y Ben David, JA Laverde-Gomez, B Dassa… - MBio, 2015 - Am Soc Microbiol
Ruminococcus bromii is a dominant member of the human gut microbiota that plays a key
role in releasing energy from dietary starches that escape digestion by host enzymes via its …

Resistant starch, microbiome, and precision modulation

PA Dobranowski, A Stintzi - Gut Microbes, 2021 - Taylor & Francis
Resistant starch, microbiome, and precision modulation. Mounting evidence has positioned
the gut microbiome as a nexus of health. Modulating its phylogenetic composition and …

Carbohydrate-binding modules facilitate the enzymatic hydrolysis of lignocellulosic biomass: Releasing reducing sugars and dissociative lignin available for …

Q Shi, AM Abdel-Hamid, Z Sun, Y Cheng, T Tu… - Biotechnology …, 2023 - Elsevier
The microbial decomposition and utilization of lignocellulosic biomass present in the plant
tissues are driven by a series of carbohydrate active enzymes (CAZymes) acting in concert …

The carbohydrate‐binding module family 20–diversity, structure, and function

C Christiansen, M Abou Hachem, Š Janeček… - The FEBS …, 2009 - Wiley Online Library
Starch‐active enzymes often possess starch‐binding domains (SBDs) mediating attachment
to starch granules and other high molecular weight substrates. SBDs are divided into nine …