With the changing disease spectrum, atherosclerosis has become increasingly prevalent
worldwide and the associated diseases have emerged as the leading cause of death. Due …

Programmed cell death (PCD) is a controlled and organized form of death regulated by
genes, allowing cells to adapt to their environment. Pyroptosis, a recently discovered type of …

Perioperative neurocognitive disorders (PNDs) are frequent complications associated with
cognitive impairment during the perioperative period, including acute postoperative delirium …

The gasdermin (GSDM) family has garnered significant attention for its pivotal role in
immunity and disease as a key player in pyroptosis. This recently characterized class of pore …

Inflammation is a crucial factor in cardiac remodeling after acute myocardial infarction (MI).
Neutrophils, as the first wave of leukocytes to infiltrate the injured myocardium, exacerbate …

Sepsis is a life-threatening multi-organ dysfunction syndrome caused by an abnormal host
response to infection. Regulated cell death is essential for maintaining tissue homeostasis …

Background Alopecia affects patients' appearance and psychology. Mixed-lineage kinase
domain-like pseudokinase (MLKL)-mediated necrosis plays a role in various skin diseases …

This study aimed to determine the cardioprotective effect of necrosulfonamide (NSA), a
pyroptosis and necroptosis inhibitor, against acute doxorubicin cardiotoxicity. Fifteen male …

Background: Cardiovascular and cerebrovascular diseases are major global health
problems, and the main cause is atherosclerosis. Recently, molecular imaging has been …