Emerging roles and functional mechanisms of PIWI-interacting RNAs
X Wang, A Ramat, M Simonelig, MF Liu - Nature Reviews Molecular …, 2023 - nature.com
PIWI-interacting RNAs (piRNAs) are a class of small non-coding RNAs that associate with
proteins of the PIWI clade of the Argonaute family. First identified in animal germ line cells …
proteins of the PIWI clade of the Argonaute family. First identified in animal germ line cells …
PIWI-interacting RNA: its biogenesis and functions
YW Iwasaki, MC Siomi, H Siomi - Annual review of biochemistry, 2015 - annualreviews.org
PIWI-interacting RNAs (piRNAs) are a class of small RNAs that are 24–31 nucleotides in
length. They associate with PIWI proteins, which constitute a germline-specific subclade of …
length. They associate with PIWI proteins, which constitute a germline-specific subclade of …
PIWI-interacting small RNAs: the vanguard of genome defence
PIWI-interacting RNAs (piRNAs) are a distinct class of small non-coding RNAs that form the
piRNA-induced silencing complex (piRISC) in the germ line of many animal species. The …
piRNA-induced silencing complex (piRISC) in the germ line of many animal species. The …
RNA interference: biology, mechanism, and applications
N Agrawal, PVN Dasaradhi, A Mohmmed… - Microbiology and …, 2003 - Am Soc Microbiol
Double-stranded RNA-mediated interference (RNAi) is a simple and rapid method of
silencing gene expression in a range of organisms. The silencing of a gene is a …
silencing gene expression in a range of organisms. The silencing of a gene is a …
[HTML][HTML] Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing
A Grishok, AE Pasquinelli, D Conte, N Li, S Parrish… - Cell, 2001 - cell.com
RNAi is a gene-silencing phenomenon triggered by double-stranded (ds) RNA and involves
the generation of 21 to 26 nt RNA segments that guide mRNA destruction. In Caenorhabditis …
the generation of 21 to 26 nt RNA segments that guide mRNA destruction. In Caenorhabditis …
Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi
Eukaryotic heterochromatin is characterized by a high density of repeats and transposons,
as well as by modified histones, and influences both gene expression and chromosome …
as well as by modified histones, and influences both gene expression and chromosome …
MIWI2 is essential for spermatogenesis and repression of transposons in the mouse male germline
MA Carmell, A Girard, HJG Van De Kant, D Bourc'his… - Developmental cell, 2007 - cell.com
Summary Small RNAs associate with Argonaute proteins and serve as sequence-specific
guides for regulation of mRNA stability, productive translation, chromatin organization, and …
guides for regulation of mRNA stability, productive translation, chromatin organization, and …
The rde-1 gene, RNA interference, and transposon silencing in C. elegans
Double-stranded (ds) RNA can induce sequence-specific inhibition of gene function in
several organisms. However, both the mechanism and the physiological role of the …
several organisms. However, both the mechanism and the physiological role of the …
Revealing the world of RNA interference.
CC Mello, D Conte Jr - Nature, 2004 - nature.com
The recent discoveries of RNA interference and related RNA silencing pathways have
revolutionized our understanding of gene regulation. RNA interference has been used as a …
revolutionized our understanding of gene regulation. RNA interference has been used as a …
The small RNA profile during Drosophila melanogaster development
Small RNAs ranging in size between 20 and 30 nucleotides are involved in different types of
regulation of gene expression including mRNA degradation, translational repression, and …
regulation of gene expression including mRNA degradation, translational repression, and …