[HTML][HTML] PRRSV structure, replication and recombination: Origin of phenotype and genotype diversity

MA Kappes, KS Faaberg - Virology, 2015 - Elsevier
Porcine reproductive and respiratory disease virus (PRRSV) has the intrinsic ability to adapt
and evolve. After 25 years of study, this persistent pathogen has continued to frustrate efforts …

Challenges for porcine reproductive and respiratory syndrome virus (PRRSV) vaccinology

TG Kimman, LA Cornelissen, RJ Moormann… - Vaccine, 2009 - Elsevier
Porcine reproductive and respiratory syndrome virus (PRRSV) continues to be a threat for
the pig industry. Vaccines have been developed, but these failed to provide sustainable …

Porcine reproductive and respiratory syndrome viruses (porcine arteriviruses)

JJ Zimmerman, SA Dee, DJ Holtkamp… - Diseases of …, 2019 - Wiley Online Library
Control of porcine reproductive and respiratory syndrome virus (PRRSV) remains
problematic, and economic studies have uniformly shown that PRRSV inflicts major losses …

Porcine reproductive and respiratory syndrome virus nonstructural protein 1β modulates host innate immune response by antagonizing IRF3 activation

LK Beura, SN Sarkar, B Kwon, S Subramaniam… - Journal of …, 2010 - Am Soc Microbiol
Porcine reproductive and respiratory syndrome virus (PRRSV) infection of swine leads to a
serious disease characterized by a delayed and defective adaptive immune response. It is …

Pathogenesis and control of the Chinese highly pathogenic porcine reproductive and respiratory syndrome virus

J Han, L Zhou, X Ge, X Guo, H Yang - Veterinary microbiology, 2017 - Elsevier
Porcine reproductive and respiratory syndrome virus (PRRSV) has remained a major threat
to the worldwide swine industry ever since its first discovery in the early 1990s. Under the …

Porcine reproductive and respiratory syndrome modified live virus vaccine: a “leaky” vaccine with debatable efficacy and safety

L Zhou, X Ge, H Yang - Vaccines, 2021 - mdpi.com
Porcine reproductive and respiratory syndrome (PRRS) caused by the PRRS virus (PRRSV)
is one of the most economically important diseases, that has significantly impacted the …

Molecular and cellular mechanisms for PRRSV pathogenesis and host response to infection

TQ An, JN Li, CM Su, D Yoo - Virus research, 2020 - Elsevier
Porcine reproductive and respiratory syndrome virus (PRRSV) has caused tremendous
amounts of economic losses to the swine industry for more than three decades, but its …

The role of porcine reproductive and respiratory syndrome (PRRS) virus structural and non-structural proteins in virus pathogenesis

N Music, CA Gagnon - Animal health research reviews, 2010 - cambridge.org
Porcine reproductive and respiratory syndrome (PRRS) is an economically devastating viral
disease affecting the swine industry worldwide. The etiological agent, PRRS virus (PRRSV) …

Interplay between interferon-mediated innate immunity and porcine reproductive and respiratory syndrome virus

Y Sun, M Han, C Kim, JG Calvert, D Yoo - Viruses, 2012 - mdpi.com
Innate immunity is the first line of defense against viral infection, and in turn, viruses have
evolved to evade host immune surveillance. As a result, viruses may persist in host and …

[HTML][HTML] Macrophage polarization in virus-host interactions

Y Sang, LC Miller, F Blecha - Journal of clinical & cellular …, 2015 - ncbi.nlm.nih.gov
Macrophage involvement in viral infections and antiviral states is common. However, this
involvement has not been well-studied in the paradigm of macrophage polarization, which …