A ubiquitously expressed cytokine, transforming growth factor-beta (TGF-β) plays a
significant role in various ongoing cellular mechanisms. The gain or loss-of-function of TGF …

JAK/STAT signaling pathway is one of the important regulatory signaling cascades for the
myriad of cellular processes initiated by various types of ligands such as growth factors …

When small proteins such as cytokines bind to their associated receptors on the plasma
membrane, they can activate multiple internal signaling cascades allowing information from …

Gastric cancer (GC) is a leading type of cancer. Although immunotherapy has yielded
important recent progress in the treatment of GC, the prognosis remains poor due to drug …

Gastric cancer (GC) is the fifth most common cancer worldwide and makes up a significant
component of the global cancer burden. Helicobacter pylori (H. pylori) is the most influential …

Cytokines are proteins that act in the immune response and inflammation and have been
associated with the development of some types of cancer, such as gastric cancer (GC). GC …

Helicobacter pylori (H. pylori) colonizes the stomach and leads to the secretion of a vast
range of cytokines by infiltrated leukocytes directing immune/inflammatory response against …

Purpose Helicobacter pylori (H. pylori) is a significant risk factor for development of gastric
cancer (GC), one of the deadliest malignancies in the world. However, the mechanism by …

Background Helicobacter pylori infection is considered as the major risk factor for gastric
adenocarcinoma. Today, the increasing emergence of antibiotic-resistant strains has …

Objective Helicobacter pylori (H. pylori) is a major risk factor for the stomach
adenocarcinoma (STAD). This study aimed to investigate the potential role of a H. pylori …