All endocrine glands are susceptible to neoplastic growth, yet the health consequences of
these neoplasms differ between endocrine tissues. Pituitary neoplasms are highly prevalent …

Although usually benign, anterior pituitary tumours occasionally exhibit aggressive
behaviour, with invasion of surrounding tissues, rapid growth, resistance to conventional …

Pituitary neuroendocrine tumors (PitNETs) are common, with five main histological subtypes:
lactotroph, somatotroph, and thyrotroph (POU1F1/PIT1 lineage); corticotroph (TBX19/TPIT …

Pituitary neuroendocrine tumor (PitNET) is one of the most common intracranial tumors. Due
to its extensive tumor heterogeneity and the lack of high-quality tissues for biomarker …

Substantial advances have been made recently in the pathobiology of pituitary tumors.
Similar to many other endocrine tumors, over the last few years we have recognized the role …

Context Pituitary carcinoma is a rare and aggressive malignancy with a poor prognosis and
few effective treatment options. Case A 35-year-old woman presented with an aggressive …

Purpose: Pituitary adenomas are one of the most common benign neoplasms of the central
nervous system. Although emerging evidence suggests roles for both genetic and …

Cushing's disease results from corticotroph adenomas of the pituitary that hypersecrete
adrenocorticotropin (ACTH), leading to excess glucocorticoid and hypercortisolism …

Abstract Background Medical treatment in Cushing's disease (CD) is limited due to poor
understanding of its pathogenesis. Pathogenic variants of ubiquitin specific peptidase 8 …

Human oncoproteins promote transformation of cells into tumours by dysregulating the
signalling pathways that are involved in cell growth, proliferation and death. Although …