Abstract Death receptor 3 (DR3) and its corresponding ligand, tumor necrosis factor‑like
ligand 1A (TL1A), belong to the tumor necrosis factor superfamily. Signaling via this receptor …

Cervical squamous cell carcinoma is one of the most common causes of female cancer
deaths worldwide. At present, immunotherapy using immune checkpoint blockade (ICB) has …

Diverticular disease is a common condition among the elderly, with a steady increase in
prevalence over time. Also, it has a temporal, geographic, and ethnic variation in incidence …

Breast cancer is the most common type of cancer in Egyptian females. Polymorphisms in the
angiogenesis pathway have been implicated previously in cancer risk and prognosis. The …

Similar to the behavior of inflamed tubular epithelial cells, clear cell renal cell carcinoma
(ccRCC) cells express death receptor 3 (DR3 or TNFSFR25) in situ, and expression …

Background Tumor necrosis factor receptor superfamily 25 (TNFRSF25) is a T-cell co-
stimulatory receptor. Expression of its ligand, TNF-like cytokine 1A (TL1A), on mouse tumor …

肿瘤坏死因子超家族成员15 (TNFSF15) 主要是由血管内皮细胞特异分泌的细胞因子.
作为死亡受体3 (DR3) 的配体, 它参与调控VEGF/VEGFR 信号通路, 进而影响多种脉管细胞的 …

For patients with cirrhosis, early diagnosis is the key to delaying the development of liver
fibrosis and improving prognosis. This study aimed to investigate the clinical significance of …

Tumour necrosis family superfamily (TNFSF) member 15 (TNFSF15), encoded by TNFSF15,
regulates immune responses and inflammation. However, the roles of TNFSF15 single …

Functional genomics, a multidisciplinary subject, investigates the functions of genes and
their products in biological systems to better understand diseases and find new drugs. Drug …