Pancreatic cancer is an increasingly common cause of cancer mortality with a tight
correspondence between disease mortality and incidence. Furthermore, it is usually …

Given that the PI3K/AKT pathway has manifested its compelling influence on multiple
cellular process, we further review the roles of hyperactivation of PI3K/AKT pathway in …

Glioblastoma is the most common primary intracranial malignant tumor in adults and has
high morbidity and high mortality. TMEM158 has been reported to promote the progression …

As one of the malignancies with high mortality and high insensitivity to existing therapies,
pancreatic cancer and mechanisms underlying its progression have received growing …

Pancreatic cancer (PC) is an aggressive malignant tumor with low rate of surgical resection
and poor prognosis. Transforming growth factor-β (TGF-β) is a cytokine that has both …

Background Membrane protein TMEM158 was initially reported as a Ras-induced gene
during senescence and has been implicated as either an oncogenic factor or tumor …

Abstract Alpha-1, 6 fucosylation of N-glycans (core fucosylation, CF) represents a unique
form of N-glycans and is widely involved in disease progression. In order to accurately …

Triple-negative breast cancer (TNBC) is a highly aggressive form of breast cancer with high
metastatic potential. To date, no directed treatment options have been developed for the …

Transmembrane proteins (TMEM) are located in the different biological membranes of the
cell and have at least one passage through these cellular compartments. TMEM proteins …

The purpose of this study was to investigate the expression significance, predictive value,
immunologic function, and biological role of transmembrane protein 158 (TMEM158) in the …