The gut and lungs are anatomically distinct, but potential anatomic communications and
complex pathways involving their respective microbiota have reinforced the existence of a …

The revolution in microbiota research over the past decade has provided invaluable
knowledge about the function of the microbial species that inhabit the human body. It has …

This review will describe the structure and function of the eosinophil. The roles of several
relevant cell surface molecules and receptors will be discussed. We will also explore the …

Background Chronic airway inflammation is the main driver of pathogenesis in respiratory
diseases such as severe asthma, chronic obstructive pulmonary disease, cystic fibrosis (CF) …

There has been long-standing interest in the role of bacterial communities in the complex
and heterogeneous disease of asthma. With the advent of 16s rRNA sequencing replacing …

Background While there seems to be a consensus that a decrease in gut microbiome
diversity is related to a decline in health status, the associations between respiratory …

Over the last few decades, advances in our understanding of microbial ecology have
allowed us to appreciate the important role of microbial communities in maintaining human …

The importance of the microbiome, and of the gut-lung axis in the origin and persistence of
asthma, is an ongoing field of investigation. The process of microbial colonisation in the first …

Asthma is a highly heterogeneous disease, often manifesting with wheeze, dyspnea, chest
tightness, and cough as prominent symptoms. The eliciting factors, natural history …

Airway inflammation plays a key role in asthma pathogenesis but is heterogeneous in
nature. There has been significant scientific discovery with regard to type 2-driven …