[HTML][HTML] Social brain, social dysfunction and social withdrawal

S Porcelli, N Van Der Wee, S van der Werff… - Neuroscience & …, 2019 - Elsevier
The human social brain is complex. Current knowledge fails to define the neurobiological
processes underlying social behaviour involving the (patho-) physiological mechanisms that …

[HTML][HTML] The anatomy of apathy: a neurocognitive framework for amotivated behaviour

C Le Heron, MAJ Apps, M Husain - Neuropsychologia, 2018 - Elsevier
Apathy is a debilitating syndrome associated with many neurological disorders, including
several common neurodegenerative diseases such as Parkinson's disease and Alzheimer's …

Diagnostic criteria for apathy in neurocognitive disorders

DS Miller, P Robert, L Ereshefsky, L Adler… - Alzheimer's & …, 2021 - Wiley Online Library
Introduction Apathy is common in neurocognitive disorders (NCD) but NCD‐specific
diagnostic criteria are needed. Methods The International Society for CNS Clinical Trials …

Apathy and anxiety are early markers of Alzheimer's disease

M Johansson, E Stomrud, O Lindberg, E Westman… - Neurobiology of …, 2020 - Elsevier
In this study, we investigated associations between neuropsychiatric symptoms (ie, apathy,
anxiety, and depression) and cerebral atrophy, white matter lesions (WML), beta-amyloid …

Apathy associated with neurocognitive disorders: recent progress and future directions

KL Lanctôt, L Agüera-Ortiz, H Brodaty, PT Francis… - Alzheimer's & …, 2017 - Elsevier
Introduction Apathy is common in neurocognitive disorders (NCDs) such as Alzheimer's
disease and mild cognitive impairment. Although the definition of apathy is inconsistent in …

The neurobiology of apathy in depression and neurocognitive impairment in older adults: a review of epidemiological, clinical, neuropsychological and biological …

DC Steffens, M Fahed, KJ Manning, L Wang - Translational psychiatry, 2022 - nature.com
Apathy is a common condition that involves diminished initiative, diminished interest and
diminished emotional expression or responsiveness. It is highly prevalent in the context of a …

[HTML][HTML] Apathy in Alzheimer's disease

L Nobis, M Husain - Current opinion in behavioral sciences, 2018 - Elsevier
Highlights•Apathy is the commonest neuropsychiatric symptom in Alzheimer's disease
(AD).•Neuroimaging findings implicate frontostriatal circuits involving the anterior cingulate …

Behavioral and psychological symptoms in Alzheimer's dementia and vascular dementia

WJ Deardorff, GT Grossberg - Handbook of clinical neurology, 2019 - Elsevier
Behavioral and psychological symptoms of dementia (BPSD) are highly prevalent and
represent a significant burden for patients and their caregivers. Early recognition and …

Neural correlates of apathy in patients with neurodegenerative disorders, acquired brain injury, and psychiatric disorders

C Kos, MJ van Tol, JBC Marsman, H Knegtering… - Neuroscience & …, 2016 - Elsevier
Apathy can be described as a loss of goal-directed purposeful behavior and is common in a
variety of neurological and psychiatric disorders. Although previous studies investigated …

Physical Exercise as Disease-Modifying Alternative against Alzheimer's Disease: A Gut–Muscle–Brain Partnership

D Cutuli, D Decandia, G Giacovazzo… - International journal of …, 2023 - mdpi.com
Alzheimer's disease (AD) is a common cause of dementia characterized by
neurodegenerative dysregulations, cognitive impairments, and neuropsychiatric symptoms …