Lipids play crucial roles in signal transduction, contribute to the structural integrity of cellular
membranes, and regulate energy metabolism. Questions remain as to which lipid species …

Ulcerative colitis (UC) belongs to the group of inflammatory bowel diseases (IBD). UC is an
incurable, diffuse, and chronic inflammatory process of the colonic mucosa with alternating …

Inflammatory bowel disease (IBD) is a multifactorial disease with increasing incidence in the
US suggesting that environmental factors, including diet, are involved. It has been …

Epithelial cells (enterocytes) form part of the intestinal barrier, the largest human interface
between the internal and external environments, and responsible for maintaining regulated …

Infections and vaccines can induce enhanced long-term responses in innate immune cells,
establishing an innate immunological memory termed trained immunity. Here, we show that …

With the epidemic of human obesity, dietary fats have increasingly become a focal point of
biomedical research. Epidemiological studies indicate that high-fat diets (HFDs), especially …

Background The processing of dietary lipids in the intestinal lumen involves metabolic
processes of the host and also of the microbial organisms that reside in the gut. Whereas, in …

Inflammatory bowel disease (IBD) is an umbrella term used to describe chronic inflammatory
disorders related to a substantial reduction in the quality of life of patients. Some patients …

Abstract Background Nervonic acid (C24: 1∆ 15, 24: 1 ω-9, cis-tetracos-15-enoic acid; NA), a
long-chain monounsaturated fatty acid, plays an essential role in prevention of metabolic …

Inflammatory bowel disorders can be associated with alterations in gut microbiota
(dysbiosis) and behavioral disturbances. In experimental colitis, administration of fish oil …