[HTML][HTML] Role of gut microbiota and oxidative stress in the progression of non-alcoholic fatty liver disease to hepatocarcinoma: Current and innovative therapeutic …

A Borrelli, P Bonelli, FM Tuccillo, ID Goldfine, JL Evans… - Redox biology, 2018 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) represents the most common chronic liver disease
in industrialized countries. NAFLD progresses through the inflammatory phase of non …

Effects of gut microbes on nutrient absorption and energy regulation

R Krajmalnik‐Brown, ZE Ilhan… - Nutrition in clinical …, 2012 - Wiley Online Library
Malnutrition may manifest as either obesity or undernutrition. Accumulating evidence
suggests that the gut microbiota plays an important role in the harvest, storage, and …

Seabuckthorn polysaccharide ameliorates high-fat diet-induced obesity by gut microbiota-SCFAs-liver axis

Y Lan, Q Sun, Z Ma, J Peng, M Zhang, C Wang… - Food & Function, 2022 - pubs.rsc.org
Obesity has been reported to be associated with gut microbiome dysbiosis. seabuckthorn
fruits have traditionally been used in Tibetan foods and medicines for thousands of years …

High-fat diet-induced obesity in animal models

N Hariri, L Thibault - Nutrition research reviews, 2010 - cambridge.org
Epidemiological studies have shown a positive relationship between dietary fat intake and
obesity. Since rats and mice show a similar relationship, they are considered an appropriate …

The gut microbiota as an environmental factor that regulates fat storage

F Bäckhed, H Ding, T Wang… - Proceedings of the …, 2004 - National Acad Sciences
New therapeutic targets for noncognitive reductions in energy intake, absorption, or storage
are crucial given the worldwide epidemic of obesity. The gut microbial community …

The gut microbiota and its relationship to diet and obesity: new insights

SF Clarke, EF Murphy, K Nilaweera, PR Ross… - Gut …, 2012 - Taylor & Francis
Obesity develops from a prolonged imbalance of energy intake and energy expenditure.
However, the relatively recent discovery that the composition and function of the gut …

Mechanisms underlying the resistance to diet-induced obesity in germ-free mice

F Bäckhed, JK Manchester… - Proceedings of the …, 2007 - National Acad Sciences
The trillions of microbes that colonize our adult intestines function collectively as a metabolic
organ that communicates with, and complements, our own human metabolic apparatus …

[PDF][PDF] Cirrhosis regression is associated with improved clinical outcomes in patients with nonalcoholic steatohepatitis

AJ Sanyal, QM Anstee, M Trauner, EJ Lawitz… - …, 2022 - Wiley Online Library
Abstract Background and Aims Surrogate endpoints that predict complications are
necessary for assessment and approval of NASH therapies. We assessed associations …

Lipoprotein lipase: from gene to obesity

H Wang, RH Eckel - American Journal of Physiology …, 2009 - journals.physiology.org
Lipoprotein lipase (LPL) is a multifunctional enzyme produced by many tissues, including
adipose tissue, cardiac and skeletal muscle, islets, and macrophages. LPL is the rate …

Effects of resveratrol on gut microbiota and fat storage in a mouse model with high-fat-induced obesity

Y Qiao, J Sun, S Xia, X Tang, Y Shi, G Le - Food & function, 2014 - pubs.rsc.org
Recent studies have investigated the anti-obesity effect of resveratrol, but the pathways
through which resveratrol resists obesity are not clear. In the present study, we hypothesize …