Metastasis accounts for the majority of cancer-associated mortalities, representing a huge
health and economic burden. One of the mechanisms that enables metastasis is …

Mesenchymal stromal/stem cells (MSCs) are used in many studies due to their therapeutic
potential, including their differentiative ability and immunomodulatory properties. These cells …

Background Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers.
Despite the successful application of immune checkpoint blockade in a range of human …

Despite recent advances in cancer immunotherapy, pancreatic ductal adenocarcinoma
(PDAC) remains unresponsive due to an immunosuppressive tumor microenvironment …

The epigenetic regulation of N6-methyladenosine (m6A) has attracted considerable interest
in tumor research, but the potential roles of m6A regulator-related genes, remain largely …

Advances in immunotherapy have revolutionized cancer treatment, yet many patients do not
show clinical responses. While most immunotherapies target T cells, myeloid cells are the …

Background Thyroid nodule (TN) patients in China are subject to overdiagnosis and
overtreatment. The implementation of existing technologies such as thyroid ultrasonography …

Since the advent of computing, humans have sought computer input technologies that are
expressive, intuitive, and universal. While diverse modalities have been developed …

Despite the curative potential of checkpoint blockade immunotherapy, a majority of patients
remain unresponsive to existing treatments. Glyco-immune checkpoints–interactions of cell …

Adoptive cell therapy (ACT) using Chimeric Antigen Receptor (CAR) and T Cell Receptor
(TCR) engineered T cells represents an innovative therapeutic approach for the treatment of …