Neuronal cell death mechanisms in major neurodegenerative diseases
Neuronal cell death in the central nervous system has always been a challenging process to
decipher. In normal physiological conditions, neuronal cell death is restricted in the adult …
decipher. In normal physiological conditions, neuronal cell death is restricted in the adult …
The role of noradrenaline in cognition and cognitive disorders
Many aspects of cognition and behaviour are regulated by noradrenergic projections to the
forebrain originating from the locus coeruleus, acting through alpha and beta …
forebrain originating from the locus coeruleus, acting through alpha and beta …
The mechanistic link between selective vulnerability of the locus coeruleus and neurodegeneration in Alzheimer's disease
Alzheimer's disease (AD) is neuropathologically characterized by the intracellular
accumulation of hyperphosphorylated tau and the extracellular deposition of amyloid-β …
accumulation of hyperphosphorylated tau and the extracellular deposition of amyloid-β …
Multi-modal deep learning model for auxiliary diagnosis of Alzheimer's disease
F Zhang, Z Li, B Zhang, H Du, B Wang, X Zhang - Neurocomputing, 2019 - Elsevier
Alzheimer's disease (AD) is one of the most difficult to cure diseases. Alzheimer's disease
seriously affects the normal lives of the elderly and their families. The mild cognitive …
seriously affects the normal lives of the elderly and their families. The mild cognitive …
Cholesterol and Alzheimer's disease risk: a meta-meta-analysis
O Sáiz-Vazquez, A Puente-Martínez, S Ubillos-Landa… - Brain sciences, 2020 - mdpi.com
Background: Alzheimer's disease (AD) is the most common subtype of dementia. In the last
ten years, the relationship between cholesterol and AD has been investigated. Evidence …
ten years, the relationship between cholesterol and AD has been investigated. Evidence …
[HTML][HTML] An effective multimodal image fusion method using MRI and PET for Alzheimer's disease diagnosis
Alzheimer's disease (AD) is an irreversible brain disease that severely damages human
thinking and memory. Early diagnosis plays an important part in the prevention and …
thinking and memory. Early diagnosis plays an important part in the prevention and …
[HTML][HTML] The endoplasmic reticulum stress and unfolded protein response in Alzheimer's disease: a calcium dyshomeostasis perspective
Protein misfolding is prominent in early cellular pathology of Alzheimer's disease (AD),
implicating pathophysiological significance of endoplasmic reticulum stress/unfolded protein …
implicating pathophysiological significance of endoplasmic reticulum stress/unfolded protein …
NLRP1 Inflammasome activation in the hippocampal formation in Alzheimer's disease: Correlation with neuropathological changes and unbiasedly estimated …
Neuroinflammation is one of the core pathological features of Alzheimer's disease (AD) as
both amyloid β (Aβ) and tau monomers and oligomers can trigger the long-term pro …
both amyloid β (Aβ) and tau monomers and oligomers can trigger the long-term pro …
Human tau-overexpressing mice recapitulate brainstem involvement and neuropsychiatric features of early Alzheimer's disease
KM Khan, N Balasubramanian, G Gaudencio… - Acta neuropathologica …, 2023 - Springer
Alzheimer's disease (AD) poses an ever-increasing public health concern as the population
ages, affecting more than 6 million Americans. AD patients present with mood and sleep …
ages, affecting more than 6 million Americans. AD patients present with mood and sleep …
Multi-modal biomarkers of repetitive head impacts and traumatic encephalopathy syndrome: A clinicopathological case series
Traumatic encephalopathy syndrome (TES) criteria were developed to aid diagnosis of
chronic traumatic encephalopathy (CTE) pathology during life. Interpreting clinical and …
chronic traumatic encephalopathy (CTE) pathology during life. Interpreting clinical and …