Immunology of COVID‐19: mechanisms, clinical outcome, diagnostics, and perspectives—a report of the European Academy of Allergy and Clinical Immunology …
With the worldwide spread of the novel severe acute respiratory syndrome coronavirus‐2
(SARS‐CoV‐2) resulting in declaration of a pandemic by the World Health Organization …
(SARS‐CoV‐2) resulting in declaration of a pandemic by the World Health Organization …
The activation of bystander CD8+ T cells and their roles in viral infection
During viral infections, significant numbers of T cells are activated in a T cell receptor-
independent and cytokine-dependent manner, a phenomenon referred to as “bystander …
independent and cytokine-dependent manner, a phenomenon referred to as “bystander …
Regulation of antiviral T cell responses by type I interferons
Type I interferons (IFNs) are pro-inflammatory cytokines that are rapidly induced in different
cell types during viral infections. The consequences of type I IFN signalling include direct …
cell types during viral infections. The consequences of type I IFN signalling include direct …
T cell-mediated immune response to respiratory coronaviruses
R Channappanavar, J Zhao, S Perlman - Immunologic research, 2014 - Springer
Emerging respiratory coronaviruses such as the severe acute respiratory syndrome
coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV) …
coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV) …
Immune responses during COVID-19 infection
C Melenotte, A Silvin, AG Goubet, I Lahmar… - …, 2020 - Taylor & Francis
Over the past 16 years, three coronaviruses (CoVs), severe acute respiratory syndrome CoV
(SARS-CoV) in 2002, Middle East respiratory syndrome CoV (MERS-CoV) in 2012 and …
(SARS-CoV) in 2002, Middle East respiratory syndrome CoV (MERS-CoV) in 2012 and …
Temporal analysis of early immune responses in patients with acute hepatitis B virus infection
C Dunn, D Peppa, P Khanna, G Nebbia, M Jones… - Gastroenterology, 2009 - Elsevier
BACKGROUND & AIMS: Hepatitis B virus (HBV) causes more than 1 million deaths annually
from immune-mediated liver damage. The long incubation period has been difficult to study; …
from immune-mediated liver damage. The long incubation period has been difficult to study; …
Endogenous naive CD8+ T cell precursor frequency regulates primary and memory responses to infection
Through genetic recombination, the adaptive immune system generates a diverse T cell
repertoire allowing recognition of a vast spectrum of foreign antigens. Any given CD8+ T cell …
repertoire allowing recognition of a vast spectrum of foreign antigens. Any given CD8+ T cell …
Heterologous immunity between viruses
RM Welsh, JW Che, MA Brehm… - Immunological reviews, 2010 - Wiley Online Library
Immune memory responses to previously encountered pathogens can sometimes alter the
immune response to and the course of infection of an unrelated pathogen by a process …
immune response to and the course of infection of an unrelated pathogen by a process …
Redox regulation of T-cell function: from molecular mechanisms to significance in human health and disease
P Kesarwani, AK Murali, AA Al-Khami… - Antioxidants & redox …, 2013 - liebertpub.com
Reactive oxygen species (ROS) are thought to have effects on T-cell function and
proliferation. Low concentrations of ROS in T cells are a prerequisite for cell survival, and …
proliferation. Low concentrations of ROS in T cells are a prerequisite for cell survival, and …
Oncolytic virus-derived type I interferon restricts CAR T cell therapy
L Evgin, AL Huff, P Wongthida, J Thompson… - Nature …, 2020 - nature.com
The application of adoptive T cell therapies, including those using chimeric antigen receptor
(CAR)-modified T cells, to solid tumors requires combinatorial strategies to overcome …
(CAR)-modified T cells, to solid tumors requires combinatorial strategies to overcome …