The appearance of multicellular organisms imposed the development of several
mechanisms for cell-to-cell communication, whereby different types of cells coordinate their …

Gap junctions (GJ), specialised membrane structures that mediate cell-to-cell
communication in almost all animal tissues, are composed of intercellular channel-forming …

Pannexin 1 (Panx1), an ortholog to invertebrate innexin gap junctions, has recently been
proposed to be the pore induced by P2X7 receptor (P2X7R) activation. We explored the …

A genetic polymorphism in the human gene encoding connexin37 (CX37, encoded by
GJA4, also known as CX37) has been reported as a potential prognostic marker for …

The P2X 7 nucleotide receptor (P2X 7 R) is an ATP-gated ion channel expressed in many
cell types including osteoblasts and osteocytes. Mice with a null mutation of P2X 7 R have …

The advent of multicellular organisms, some 800 million years ago, necessitated the
development of mechanisms for cell-to-cell synchronization and for the spread of signals …

purpose. Intercellular Ca 2+ wave propagation is a distinct form of cell–cell communication.
In corneal endothelial cells, intercellular Ca 2+ wave propagation evoked by a point …

Connexins are integral membrane building blocks that form gap junctions, enabling direct
cytoplasmic exchange of ions and low-molecular-mass metabolites between adjacent cells …

Gap junctional channels are a class of membrane channels composed of transmembrane
channel-forming integral membrane proteins termed connexins, innexins or pannexins that …

Abstract P2X receptor (P2XR) is a family of the ATP-gated ion channel family and can
permeabilize the plasma membrane to small cations such as potassium, sodium, and …