Estrogen is a fundamental regulator of the metabolic system of the female brain and body.
Within the brain, estrogen regulates glucose transport, aerobic glycolysis, and mitochondrial …

Alzheimer's disease and other related neurodegenerative diseases are highly debilitating
disorders that affect millions of people worldwide. Efforts towards developing effective …

Being isolated from the peripheral system by the blood–brain barrier, the brain has long
been considered a completely impervious tissue. However, recent findings show that the gut …

Ghrelin is an octanoylated peptide that acts via its specific receptor, the growth hormone
secretagogue receptor type 1a (GHSR-1a), and regulates a vast variety of physiological …

Alzheimer's disease (AD) is a central nervous system disease that can lead to cognitive
impairment and progressive memory loss. An increasing number of studies have shown that …

Alzheimer's disease (AD) is an age-related neurodegenerative disorder characterized by
cognitive deficits and neuronal loss. Deposition of beta-amyloid peptide (Aβ) causes …

Alzheimer's disease (AD) is an age-related neurological disorder characterized by the
deposition of amyloid-β (Aβ), cognitive deficits, and neuronal loss. The decline in …

Ghrelin is a 28-amino-acid peptide hormone, first described in 1999 and broadly expressed
in the organism. As the only known orexigenic hormone secreted in the periphery, it …

Chromatin acetylation, a critical regulator of synaptic plasticity and memory processes, is
thought to be altered in neurodegenerative diseases. Here, we demonstrate that spatial …

Cognitive enhancers (nootropics) are drugs to treat cognition deficits in patients suffering
from Alzheimer's disease, schizophrenia, stroke, attention deficit hyperactivity disorder, or …