Discovery of a Novel Photocaged PI3K Inhibitor Capable of Real-Time Reporting of Drug Release

H Tian, S You, T Xiong, M Ji, K Zhang… - ACS Medicinal …, 2023 - ACS Publications
A novel photocaged PI3K inhibitor 2 was designed and synthesized by introducing a
cascade photocaging group to block its key interaction with the kinase. Upon UV light …