Hypericin and its anticancer effects: From mechanism of action to potential therapeutic application
N Choudhary, TE Collignon, D Tewari, A Bishayee - Phytomedicine, 2022 - Elsevier
Background Emerging studies indicate that hypericin has diverse pharmacological actions
and exhibits potential for treatment of various types of cancer. Purpose The current review …
and exhibits potential for treatment of various types of cancer. Purpose The current review …
[HTML][HTML] Computer-aided drug design in anti-cancer drug discovery: what have we learnt and what is the way forward??
The escalating prevalence of cancer on a global scale, coupled with the inadequacies of
present-day therapies and the emergence of drug-resistant cancer strains, has necessitated …
present-day therapies and the emergence of drug-resistant cancer strains, has necessitated …
Orange peel as source of nutraceuticals
A Nazir, N Itrat, A Shahid, Z Mushtaq… - Food and Agricultural …, 2022 - Springer
In line with global paradigm shift towards the promotion of environmentally friendly and
sustainable solutions to prevailing challenges in all facets of human endeavor, it has …
sustainable solutions to prevailing challenges in all facets of human endeavor, it has …
Repurposing immune boosting and anti-viral efficacy of Parkia bioactive entities as multi-target directed therapeutic approach for SARS-CoV-2: exploration of lead …
The COVID-19 pandemic has caused adverse health (severe respiratory, enteric and
systemic infections) and environmental impacts that have threatened public health and the …
systemic infections) and environmental impacts that have threatened public health and the …
Banana peel as a source of nutraceuticals
BO Adetuyi, AE Ogundipe, OO Ogunlana… - Food and agricultural …, 2022 - Springer
Banana is a staple fruit because it is available all through the year and it also serves as a
source of income and food to a great number of people. Banana peel is the major byproduct …
source of income and food to a great number of people. Banana peel is the major byproduct …
Repurposing of phyto-ligand molecules from the honey bee products for Alzheimer's disease as novel inhibitors of BACE-1: Small molecule bioinformatics strategies …
N Nisa, B Rasmita, C Arati, C Uditraj… - … Science and Pollution …, 2023 - Springer
Alzheimer's disease (AD) is one of the neurodegenerative diseases, manifesting dementia,
spatial disorientation, language, cognitive, and functional impairment, mainly affects the …
spatial disorientation, language, cognitive, and functional impairment, mainly affects the …
Discovery of benzimidazole-indazole derivatives as potent FLT3-tyrosine kinase domain mutant kinase inhibitors for acute myeloid leukemia
B Ko, Y Jang, MH Kim, TT Lam, HK Seo… - European Journal of …, 2023 - Elsevier
The FMS-like tyrosine kinase 3 (FLT3) gene encodes a class III receptor tyrosine kinase that
is expressed in hematopoietic stem cells. The mutations of FLT3 gene found in 30% of acute …
is expressed in hematopoietic stem cells. The mutations of FLT3 gene found in 30% of acute …
[PDF][PDF] An In Silico Study: Phytochemical Compounds Screening of Garcinia atroviridis Griff. ex T. Anders as Anti-DENV.
NS Aini, ANM Ansori, VD Kharisma… - Journal of Pure & …, 2023 - researchgate.net
Dengue virus (DENV) is still global problem and infecting millions of people a year. This
virus belongs to Flavivirus and consists of the structural and non-structural proteins including …
virus belongs to Flavivirus and consists of the structural and non-structural proteins including …
Wnt/β‐catenin signaling pathway inhibitors, glycyrrhizic acid, solanine, polyphyllin I, crocin, hypericin, tubeimoside‐1, diosmin, and rutin in medicinal plants have …
C Egbuna, KC Patrick‐Iwuanyanwu… - Food Science & …, 2023 - Wiley Online Library
Wnt/β‐catenin signaling pathway plays a role in cancer development, organogenesis, and
embryogenesis. The abnormal activation promotes cancer stem cell renewal, proliferation …
embryogenesis. The abnormal activation promotes cancer stem cell renewal, proliferation …
[HTML][HTML] Evaluating the clinical significance of FLT3 mutation status in Syrian newly diagnosed acute myeloid leukemia patients with normal karyotype
Y Moualla, F Moassass, ALH Bassel, W Al-Achkar… - Heliyon, 2022 - cell.com
The FMS-like tyrosine kinase-3 internal tandem duplication (FLT3-ITD) is one of the most
prevalent mutations, affecting between 20 and 30 percent of cases in patients with acute …
prevalent mutations, affecting between 20 and 30 percent of cases in patients with acute …