Combining copper and zinc into a biosensor for anti-chemoresistance and achieving osteosarcoma therapeutic efficacy
Due to its built-up chemoresistance after prolonged usage, the demand for replacing
platinum in metal-based drugs (MBD) is rising. The first MBD approved by the FDA for …
platinum in metal-based drugs (MBD) is rising. The first MBD approved by the FDA for …
New dual inhibitors of SARS-CoV-2 based on metal complexes with Schiff-base 4-chloro-3-methyl phenyl hydrazine: Synthesis, DFT, antibacterial properties and …
This paper explores a dual inhibition of main protease (Mpro) and nonstructural protein
10/nonstructural protein 16 (NSP16) methyltransferase complex as the key targets for …
10/nonstructural protein 16 (NSP16) methyltransferase complex as the key targets for …
Synthesis, Characterization, in silico DFT, Molecular docking, ADMET Profiling Studies and Toxicity Predictions of Ag (I) Complex Derived from 4‐Aminoacetophenone
HAK Kyhoiesh, HM Hassan - ChemistrySelect, 2024 - Wiley Online Library
The reaction of the synthesized (E)‐1‐(4‐((2, 4‐dihydroxy‐6‐methylphenyl) diazenyl)
phenyl) ethan‐1‐one,(DMPDE) ligand with Ag (I) ion at room temperature resulted in the …
phenyl) ethan‐1‐one,(DMPDE) ligand with Ag (I) ion at room temperature resulted in the …
Study of novel bidentate heterocyclic amine-based metal complexes and their biological activities: cytotoxicity and antimicrobial activity evaluation
HM Fahmy, FM Abdel-Rahman, AA El-Sayed… - BMC chemistry, 2023 - Springer
Metallic antitumor drugs with heterocyclic ligands, such as novel AMI (amino methyl
imidazole) complexes [Pd (AMI) Cl2](1),[Cu (AMI) L1](2), and [Cu (AMI) L2· 2H2O](3) where …
imidazole) complexes [Pd (AMI) Cl2](1),[Cu (AMI) L1](2), and [Cu (AMI) L2· 2H2O](3) where …
[HTML][HTML] Crystal structure, Hirshfeld surface analysis, and computational study of tin (IV) complex: Insights from spectroscopic, anticancer and cytotoxic properties
C Bhaskar, N Elangovan, S Sowrirajan… - Results in …, 2023 - Elsevier
The complex di (p-methylbenzyl)(dibromo)(4, 7-diphenyl-1, 10-phenanthroline) tin (IV)
complex (B1) was synthesized and characterized. For the theoretical investigation, we used …
complex (B1) was synthesized and characterized. For the theoretical investigation, we used …
It takes two to tango, Part II: Synthesis of A-ring functionalised quinones containing two redox-active centres with antitumour activities
JC Oliveira, RL de Carvalho, HGS Sampaio… - Molecules, 2023 - mdpi.com
In 2021, our research group published the prominent anticancer activity achieved through
the successful combination of two redox centres (ortho-quinone/para-quinone or …
the successful combination of two redox centres (ortho-quinone/para-quinone or …
Solvents and their influence on electronic properties in IEFPCM solvation model, anticancer activity, and docking studies on (E)-2-((4-chlorobenzylidene) amino) …
KP Lisha, N Elangovan, KP Manoj, N Arumugam… - Journal of Molecular …, 2024 - Elsevier
Abstract The Schiff base (E)-2-((4-chlorobenzylidene) amino) phenol (4CL2AM) has been
synthesized from 4-chlorobenzaldehyde and 2-aminophenol. Spectroscopic techniques like …
synthesized from 4-chlorobenzaldehyde and 2-aminophenol. Spectroscopic techniques like …
Search for new biologically active compounds: in vitro studies of antitumor and antimicrobial activity of dirhodium (ii, ii) paddlewheel complexes
M Mitrović, MB Djukić, M Vukić, I Nikolić… - Dalton …, 2024 - pubs.rsc.org
Four neutral Rh1–Rh4 complexes of the general formula [Rh2 (CH3COO) 4L2], where L is
an N-alkylimidazole ligand, were synthesized and characterized using various …
an N-alkylimidazole ligand, were synthesized and characterized using various …
Analyzing the structure of the metal complexes of biologically active azo dye ligand
A novel azo dye ligand was created by diazotizing 4‐aminoantipyrine and then coupling it
with 2‐aminophenol as part of a methodical investigation of physiologically active …
with 2‐aminophenol as part of a methodical investigation of physiologically active …
Design, synthesis of new mixed azo-hydroxyquinoline complexes; in vitro anti-inflammatory, antifungal, antibacterial, theoretical, and molecular docking interactions …
Here, we combine the simple and readily synthesized azo-ligand [1-((4-Hydroxyphenyl) azo)-
2-naphthalenol (PNP)] with 8-hydroxyquinoline (QPH) to develop and synthesize novel Co …
2-naphthalenol (PNP)] with 8-hydroxyquinoline (QPH) to develop and synthesize novel Co …