Because the discovery of a link between mismatch repair deficiency and sporadic or
inherited human cancers characterized by microsatellite instability (MSI-H tumors), genes …

Helicobacter pylori infection leads to long-lasting chronic inflammation and represents the
most common risk factor underlying gastric cancer. Recently, new insights into the …

PTEN mutations have been reported to be frequent in endometrioid carcinomas of the
endometrium (EEC). Some correlation has been found between PTEN mutations and the …

The status of p53 was investigated in breast tumours arising in germ-line carriers of mutant
alleles of BRCA1 and BRCA2 and in a control series of sporadic breast tumours. p53 …

Microsatellite instability (MSI) is observed in 13–44% of gastric carcinoma. The etiology of
MSI in gastric carcinoma has not been clearly defined. To assess the role of mismatch repair …

Gastric cancer is the fourth leading cause of cancer-related death in the world. Two
histologically distinct types of gastric carcinoma,'intestinal'and 'diffuse', have different …

BACKGROUND Microsatellite instability (MI) is frequent in endometrial carcinomas (ECs),
but its occurrence in ovarian tumors is uncertain. Microsatellite instability positive ECs …

Gastric carcinomas with DNA replication errors (RER phenotype) display a particular
clinicopathologic profile and carry a putative favorable prognosis. The RER phenotype has …

The cellular and molecular pathology of gastric cancer and its precursors are reviewed and
discussed. Gastric carcinogenesis is a multistep phenomenon, beginning with precancerous …

Colon carcinomas with microsatellite mutator phenotype exhibit specific genetic and clinico‐
pathological features. This report describes the analysis of 63 “microsatellite instability …