Loop-mediated isothermal amplification as point-of-care diagnosis for neglected parasitic infections

C Avendaño, MA Patarroyo - International Journal of Molecular Sciences, 2020 - mdpi.com
The World Health Organisation (WHO) has placed twenty diseases into a group known as
neglected tropical diseases (NTDs), twelve of them being parasitic diseases: Chagas' …

An Overview of Tsetse Fly Repellents: Identification and Applications

OY Orubuloye, NJ Mbewe, DP Tchouassi… - Journal of Chemical …, 2024 - Springer
Tsetse flies are vectors of the parasite trypanosoma that cause the neglected tropical
diseases human and animal African trypanosomosis. Semiochemicals play important roles …

Antiparasitic and Cytotoxic Activity of Bokkosin, A Novel Diterpene-Substituted Chromanyl Benzoquinone From Calliandra portoricensis

JB Nvau, S Alenezi, MA Ungogo, IAM Alfayez… - Frontiers in …, 2020 - frontiersin.org
Calliandra portoricensis is a medicinal plant growing freely in Nigeria. It is used traditionally
to treat tuberculosis, as an anthelmintic and an abortifacient. Phytochemical fractionation …

Antischistosomal, antionchocercal and antitrypanosomal potentials of some Ghanaian traditional medicines and their constituents

EB Twumasi, PI Akazue, K Kyeremeh… - PLoS Neglected …, 2020 - journals.plos.org
Background Ghana is endemic for some neglected tropical diseases (NTDs) including
schistosomiasis, onchocerciasis and lymphatic filariasis. The major intervention for these …

Epizootiology and molecular identification of trypanosome species in livestock ruminants in The Gambia

A Kargbo, GU Ebiloma, YKE Ibrahim, GD Chechet… - Acta Parasitologica, 2022 - Springer
Abstract Introduction African Animal Trypanosomiasis (AAT) or nagana in animals, is caused
by the blood-borne parasitic protozoa called trypanosomes, and is potentially fatal. It is …

Chiral Chromatographic Isolation on Milligram Scale of the Human African Trypanosomiasis Treatment d- and l-Eflornithine

M Boberg, AC Jonson, H Leek… - ACS …, 2020 - ACS Publications
Eflornithine is a recommended treatment against the otherwise fatal parasitic disease late
stage human African trypanosomiasis (HAT), also known as Gambian sleeping sickness. It is …

Interleukin 21 is a marker of Human African Trypanosomiasis Infection and a contributor to pathology in mice

P Capewell, H Ilboudo, A Cooper, WJ Kabore, H Noyes… - medRxiv, 2024 - medrxiv.org
Background: Human African trypanosomiasis (HAT) is an important disease of sub-Saharan
Africa that is approaching elimination in many regions. However, the disease has previously …

Health work and skills in the last mile of disease elimination. Experiences from sleeping sickness health workers in South Sudan and DR Congo

JB Falisse, A Mpanya, E Surur, P Kingsley… - Global public …, 2022 - Taylor & Francis
Human African trypanosomiasis (HAT) is considered a highly promising candidate for
elimination within the next decade. This paper argues that the experiential knowledge of …

Whose elimination? Frontline workers' perspectives on the elimination of the Human African Trypanosomiasis and its anticipated consequences

JB Falisse, E Mwamba-Miaka, A Mpanya - Tropical Medicine and …, 2020 - mdpi.com
While academic literature has paid careful attention to the technological efforts―drugs, tests,
and tools for vector control―deployed to eliminate Gambiense Human African …

Comprehensive analysis of oral administration of Vitamin E on the early stage of Trypanosoma brucei brucei infection

RJ Ojo, GA Enoch, FS Adeh, LC Fompun… - Journal of Parasitic …, 2021 - Springer
Reinforcement of the body with exogenous antioxidants have been shown to mitigate the
negative effects of African trypanosomiasis on the host and contribute greatly to their …