In recent years, much progress has been made with respect to the unravelling of the
functions of peroxisomes in metabolism, and it is now well established that peroxisomes are …

Fatty acid metabolism has been widely studied in various organisms. However, fatty acid
transport has received less attention, even though it plays vital physiological roles, such as …

Background The superfamily of ABC proteins is among the largest known in nature. Its
members are mainly, but not exclusively, involved in the transport of a broad range of …

We have identified a new protein, Tim54p, located in the yeast mitochondrial inner
membrane. Tim54p is an essential import component, required for the insertion of at least …

X-linked adrenoleukodystrophy (X-ALD), an inherited peroxisomal disorder, is caused by
mutations in the ABCD1 gene encoding the peroxisomal ATP-binding cassette (ABC) …

Peroxisomes play a major role in human cellular lipid metabolism, including fatty acid β-
oxidation. The most frequent peroxisomal disorder is X-linked adrenoleukodystrophy, which …

Childhood cerebral adrenoleukodystrophy (CCER), adrenomyeloneuropathy (AMN) and
AMN with cerebral demyelination (AMN-C) are the main phenotypic variants of X-linked …

The available genomic sequences of five closely related hemiascomycetous yeast species
(Kluyveromyces lactis, Kluyveromyces waltii, Candida glabrata, Ashbya (Eremothecium) …

Peroxisomes are essential organelles involved in various metabolic processes, including
fatty acid β-oxidation. Their metabolic functions require a controlled exchange of metabolites …

Metabolism in trypanosomatids is compartmentalised with major pathways, notably
glycolysis, present in peroxisome-like organelles called glycosomes. To date, little …