Exercise mitigates endothelial pyroptosis and atherosclerosis by downregulating NEAT1 through N6-methyladenosine modifications
Q Yang, S Chen, X Wang, X Yang, L Chen… - … and Vascular Biology, 2023 - Am Heart Assoc
Background: The benefits of exercise on the cardiovascular system are widely recognized;
however, the underlying mechanisms are unknown. Here, we report the effect of the long …
however, the underlying mechanisms are unknown. Here, we report the effect of the long …
Research progress in the pathogenesis of sepsis-associated encephalopathy
Y Zhou, L Bai, W Tang, W Yang, L Sun - Heliyon, 2024 - cell.com
Sepsis is a syndrome that causes dysfunction of multiple organs due to the host's
uncontrolled response to infection and is a significant contributor to morbidity and mortality …
uncontrolled response to infection and is a significant contributor to morbidity and mortality …
[HTML][HTML] The role of long noncoding RNA (lncRNA) nuclear-enriched abundant transcript 1 (NEAT1) in immune diseases
D Jing, F Zhu, Z Xu, G Zhang, G Zhou - Transplant Immunology, 2022 - Elsevier
The long noncoding RNA (lncRNA) nuclear-enriched abundant transcript 1 (NEAT1) has
been shown to be involved in the pathogenesis of several diseases. Herein, we discuss …
been shown to be involved in the pathogenesis of several diseases. Herein, we discuss …
Neat1 promotes acute kidney injury to chronic kidney disease by facilitating tubular epithelial cells apoptosis via sequestering miR-129-5p
T Ma, H Li, H Liu, Y Peng, T Lin, Z Deng, N Jia, Z Chen… - Molecular Therapy, 2022 - cell.com
Acute kidney injury (AKI) is increasingly identified as a crucial risk factor for progression to
CKD. However, the factors governing AKI to CKD progression remain largely unknown. By …
CKD. However, the factors governing AKI to CKD progression remain largely unknown. By …
Machine learning for early prediction of sepsis-associated acute brain injury
C Ge, F Deng, W Chen, Z Ye, L Zhang, Y Ai… - Frontiers in …, 2022 - frontiersin.org
Background Sepsis-associated encephalopathy (SAE) is defined as diffuse brain
dysfunction associated with sepsis and leads to a high mortality rate. We aimed to develop …
dysfunction associated with sepsis and leads to a high mortality rate. We aimed to develop …
[HTML][HTML] Breaking the vicious cycle: Targeting the NLRP3 inflammasome for treating sepsis-associated encephalopathy
H Zhong, T Liu, Y Shang, C Huang, S Pan - Biomedicine & …, 2024 - Elsevier
Sepsis-associated encephalopathy (SAE) is a collection of clinical syndromes resulting from
sepsis and characterized by widespread brain dysfunction. The high prevalence of SAE has …
sepsis and characterized by widespread brain dysfunction. The high prevalence of SAE has …
Exploring circulating long non-coding RNAs in mild cognitive impairment patients' blood
B De Felice, C Coppola, S Bonavita, E Signoriello… - Biomedicines, 2023 - mdpi.com
Mild cognitive impairment (MCI) is a transitional clinical stage prior to dementia. Patients
with amnestic MCI have a high risk of progression toward Alzheimer's disease. Both …
with amnestic MCI have a high risk of progression toward Alzheimer's disease. Both …
[HTML][HTML] The protective effect of lncRNA NEAT1/miR-122-5p/Wnt1 axis on hippocampal damage in hepatic ischemic reperfusion young mice
Z Dong, L Jia, W Han, Y Wang, M Sheng, Y Ren… - Cellular signalling, 2023 - Elsevier
Hepatic ischemic reperfusion (HIR) is a common pathophysiological process in many
surgical procedures such as liver transplantation (LT) and hepatectomy. And it is also an …
surgical procedures such as liver transplantation (LT) and hepatectomy. And it is also an …
Circulating Exosomes from Septic Mice Activate NF-κB/MIR17HG Pathway in Macrophages
SC Wu, CS Rau, YC Wu, CJ Wu, CW Tsai, LH Huang… - Biomedicines, 2024 - mdpi.com
Circulating exosomes derived from polymicrobial sepsis contain various non-coding RNAs
and proteins. Isobaric tags for a relative or absolute quantitation proteomic analysis of the …
and proteins. Isobaric tags for a relative or absolute quantitation proteomic analysis of the …
A host immune-related LncRNA and mRNA signature as a discriminant classifier for bacterial from non-bacterial sepsis in children
C Wang, T Sun, Y Zhou, T Liu, S Feng, X Xiong, J Fan… - Heliyon, 2024 - cell.com
Background The variations in non-coding RNA alterations and the host immune response
between patients with bacterial and non-bacterial sepsis, along with their clinical …
between patients with bacterial and non-bacterial sepsis, along with their clinical …