BACKGROUND Infertility is a major issue in human reproductive health, affecting an
estimated 15% of couples worldwide. Infertility can result from disorders of sex development …

Abstract Infertility affects 8–12% of couples globally, and the male factor is a primary cause
in~ 50% of couples. Male infertility is a multifactorial reproductive disorder, which can be …

Azoospermia, which is the absence of spermatozoa in an ejaculate occurring due to defects
in sperm production, or the obstruction of the reproductive tract, affects about 1% of all men …

STUDY QUESTION Can whole-exome sequencing (WES) and in vitro validation studies
identify new causative genes associated with teratozoospermia, particularly for sperm head …

STUDY QUESTION Can any new genetic factors responsible for early embryonic arrest in
infertile patients be identified, together with the mechanism of pathogenic variants …

Spermiogenesis is a critical, post-meiotic phase of male gametogenesis, in which the proper
gene expression is essential for sperm maturation. However, the underFlying molecular …

Background Despite great advances in the prevention, diagnosis, treatment, and
management regarding hepatocellular carcinoma (HCC), the overall prognosis of HCC …

F-box proteins play essential roles in various cellular processes of spermatogenesis by
means of ubiquitylation and subsequent target protein degradation. They are the substrate …

Aim: We determined the prevalence and factors associated with couple infertility in three
hospitals in Douala, Cameroon. Methods: We conducted a cross-sectional study from …

Spermatogenic arrest is a severe form of non-obstructive azoospermia (NOA), which occurs
in 10–15% of infertile men. Interruption in spermatogenic progression at premeiotic, meiotic …