Current and future treatment of hepatocellular carcinoma: an updated comprehensive review

S Daher, M Massarwa, AA Benson… - Journal of clinical and …, 2017 - pmc.ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is among the leading causes of cancer-related mortality.
The principal treatment is surgical resection or liver transplantation, depending on whether …

Advances in radiotherapy and immunity in hepatocellular carcinoma

Y Yang, L Xiong, M Li, P Jiang, J Wang, C Li - Journal of Translational …, 2023 - Springer
Primary liver cancer is one of the most common malignant tumours worldwide; it caused
approximately 830,000 deaths in 2020. Hepatocellular carcinoma (HCC) is the most …

HNF4α regulates sulfur amino acid metabolism and confers sensitivity to methionine restriction in liver cancer

Q Xu, Y Li, X Gao, K Kang, JG Williams, L Tong… - Nature …, 2020 - nature.com
Methionine restriction, a dietary regimen that protects against metabolic diseases and aging,
represses cancer growth and improves cancer therapy. However, the response of different …

[HTML][HTML] Stereotactic body radiation therapy for hepatocellular carcinoma: From infancy to ongoing maturity

S Lewis, L Dawson, A Barry, T Stanescu, I Mohamad… - JHEP Reports, 2022 - Elsevier
Hepatocellular carcinoma (HCC) accounts for 90% of liver tumours and is one of the leading
causes of mortality. Cirrhosis due to viral hepatitis, alcohol or steatohepatitis is the major risk …

Critical signaling pathways governing hepatocellular carcinoma behavior; small molecule-based approaches

Z Farzaneh, M Vosough, T Agarwal… - Cancer cell international, 2021 - Springer
Hepatocellular carcinoma (HCC) is the second leading cause of death due to cancer.
Although there are different treatment options, these strategies are not efficient in terms of …

A classical description of subnanometer resolution by atomic features in metallic structures

S Trautmann, J Aizpurua, I Götz, A Undisz, J Dellith… - Nanoscale, 2017 - pubs.rsc.org
Recent experiments have evidenced sub-nanometer resolution in plasmonic-enhanced
probe spectroscopy. Such a high resolution cannot be simply explained using the commonly …

In vitro cell toxicity and intracellular uptake of doxorubicin exposed as a solution or liposomes: Implications for treatment of hepatocellular carcinoma

F Kullenberg, O Degerstedt, C Calitz, N Pavlović… - Cells, 2021 - mdpi.com
Cytostatic effects of doxorubicin in clinically applied doses are often inadequate and limited
by systemic toxicity. The main objective of this in vitro study was to determine the anti …

β-radiating radionuclides in cancer treatment, novel insight into promising approach

S Asadian, H Mirzaei, BA Kalantari… - Pharmacological …, 2020 - Elsevier
Targeted radionuclide therapy, known as molecular radiotherapy is a novel therapeutic
module in cancer medicine. β-radiating radionuclides have definite impact on target cells via …

The PP2A subunit PR130 is a key regulator of cell development and oncogenic transformation

M Dzulko, M Pons, A Henke, G Schneider… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Abstract Protein phosphatase 2A (PP2A) is a major serine/threonine phosphatase. This
enzyme is involved in a plethora of cellular processes, including apoptosis, autophagy, cell …

[HTML][HTML] Mechanisms of resistance to chemotherapy and radiotherapy in hepatocellular carcinoma

J Guo, L Li, B Guo, D Liu, J Shi, C Wu… - Translational Cancer …, 2018 - tcr.amegroups.org
Hepatocellular carcinoma (HCC) is an inflammation-related malignant tumor that develops
from underlying cirrhosis. As HCC is a common tumor seen in clinical practice, its prevention …