[HTML][HTML] The role of branched chain amino acids metabolic disorders in tumorigenesis and progression

J Wang, W Wang, F Zhu, Q Duan - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Branched-chain amino acids (BCAAs) are essential amino acids in human bodies. They
have complex metabolic pathways and various metabolites. Both BCAAs and its metabolites …

Amino acid metabolic reprogramming in tumor metastatic colonization

Z Wang, X Wu, HN Chen, K Wang - Frontiers in Oncology, 2023 - frontiersin.org
Metastasis is considered as the major cause of cancer death. Cancer cells can be released
from primary tumors into the circulation and then colonize in distant organs. How cancer …

[HTML][HTML] Prognoses and genomic analyses of proteasome 26S subunit, ATPase (PSMC) family genes in clinical breast cancer

TJ Kao, CC Wu, NN Phan, YH Liu, HDK Ta… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
Breast cancer is a complex disease, and several processes are involved in its development.
Therefore, potential therapeutic targets need to be discovered for these patients …

Identification of metastasis-related genes for predicting prostate cancer diagnosis, metastasis and immunotherapy drug candidates using machine learning …

YX Wang, B Ji, L Zhang, J Wang, JX He, BC Ding… - Biology Direct, 2024 - Springer
Abstract Background Prostate cancer (PCa) is the second leading cause of tumor-related
mortality in men. Metastasis from advanced tumors is the primary cause of death among …

Comparison of transcriptomic signatures between Monkeypox‐infected monkey and human cell lines

DTM Xuan, IJ Yeh, CC Wu, CY Su… - Journal of …, 2022 - Wiley Online Library
Monkeypox virus (MPV) is a smallpox‐like virus belonging to the genus Orthopoxvirus of the
family Poxviridae. Unlike smallpox with no animal reservoir identified and patients suffering …

Gene signatures of SARS-CoV/SARS-CoV-2-infected ferret lungs in short-and long-term models

HL Liu, IJ Yeh, NN Phan, YH Wu, MC Yen… - Infection, Genetics and …, 2020 - Elsevier
Coronaviruses (CoVs) consist of six strains, and the severe acute respiratory syndrome
coronavirus (SARS-CoV), newly found coronavirus (SARS-CoV-2) has rapidly spread …

Hsa-miR-21-3p associates with breast cancer patient survival and targets genes in tumor suppressive pathways

A Amirfallah, H Knutsdottir, A Arason, B Hilmarsdottir… - PloS one, 2021 - journals.plos.org
Breast cancer is the cancer most often diagnosed in women. MicroRNAs (MIRs) are short
RNA molecules that bind mRNA resulting in their downregulation. MIR21 has been shown to …

ASCT2 is a major contributor to serine uptake in cancer cells

KO Conger, C Chidley, ME Ozgurses, H Zhao, Y Kim… - Cell reports, 2024 - cell.com
The non-essential amino acid serine is a critical nutrient for cancer cells due to its diverse
biosynthetic functions. While some tumors can synthesize serine de novo, others are …

The ferroptosis signature predicts the prognosis and immune microenvironment of nasopharyngeal carcinoma

J Zhou, T Guo, L Zhou, M Bao, L Wang, W Zhou… - Scientific Reports, 2023 - nature.com
Nasopharyngeal carcinoma (NPC) is a cancer with a high metastatic rate and poor
prognosis. Growing studies suggest that ferroptosis take part in the development of tumours …

Identification of dipeptidyl peptidase (DPP) family genes in clinical breast cancer patients via an integrated bioinformatics approach

TK Choy, CY Wang, NN Phan, HD Khoa Ta, G Anuraga… - Diagnostics, 2021 - mdpi.com
Breast cancer is a heterogeneous disease involving complex interactions of biological
processes; thus, it is important to develop therapeutic biomarkers for treatment. Members of …