RNA-based therapies: A cog in the wheel of lung cancer defense

P Khan, JA Siddiqui, I Lakshmanan, AK Ganti, R Salgia… - Molecular cancer, 2021 - Springer
Lung cancer (LC) is a heterogeneous disease consisting mainly of two subtypes, non-small
cell lung cancer (NSCLC) and small cell lung cancer (SCLC), and remains the leading …

Evolution of the targeted therapy landscape for cholangiocarcinoma: Is cholangiocarcinoma the 'NSCLC'of GI oncology?

A Gupta, R Kurzrock, JJ Adashek - Cancers, 2023 - mdpi.com
Simple Summary In the past 20 years, the development of targeted therapies that can be
matched to a tumor's molecular and immune abnormalities has resulted in the improvement …

[HTML][HTML] Drug delivery systems of gefitinib for improved cancer therapy: A review

D Nagdiya, M Kumar, S Arora, T Bajaj, S Kujur, P Rana… - OpenNano, 2023 - Elsevier
Lung cancer is an uncontrolled and abnormal mass of growing cells with the highest
mortality rate in the world. Progressive lung cancer shows a robust resistance to cancer …

HER2 alterations in non-small cell lung cancer: biologico-clinical consequences and interest in therapeutic strategies

E Loeffler, J Ancel, V Dalstein, G Deslée, M Polette… - Life, 2023 - mdpi.com
Lung cancer stands as the first cause of death by cancer in the world. Despite the
improvement in patients' outcomes in the past decades through the development of …

Role of functional genomics in identifying cancer drug resistance and overcoming cancer therapy relapse

EO Mahgoub, WC Cho, M Sharifi, M Falahati… - Heliyon, 2023 - cell.com
Functional genomics is an emerging field focused on elucidating the function of genes or
proteins, which can help solve significant challenges related to reliable cancer therapy. The …

Linguistic analysis of plain language summaries and corresponding scientific summaries of Cochrane systematic reviews about oncology interventions

J Šuto, A Marušić, I Buljan - Cancer Medicine, 2023 - Wiley Online Library
Background Cochrane plain language summaries (PLSs) are an important format to present
high‐quality healthcare evidence to patients with cancer and their families. They should be …

Immunotherapy in patients with advanced non-small cell lung cancer lacking driver mutations and future perspectives

RAB De Mello, R Voscaboinik, JVP Luciano… - Cancers, 2021 - mdpi.com
Simple Summary The following paper was developed as a reference for healthcare workers
who are looking for information on advanced non-small cell lung cancers that lack driver …

Construction of an endoplasmic reticulum stress-related signature in lung adenocarcinoma by comprehensive bioinformatics analysis

Y Wang, J Nie, L Dai, W Hu, S Han, J Zhang… - BMC Pulmonary …, 2023 - Springer
Abstract Background Lung Adenocarcinoma (LUAD) is a major component of lung cancer.
Endoplasmic reticulum stress (ERS) has emerged as a new target for some tumor …

Lipid polymer hybrid nanoparticles against lung cancer and their application as inhalable formulation

SN Kassaee, D Richard, GA Ayoko, N Islam - Nanomedicine, 2024 - Taylor & Francis
Lung cancer is a leading cause of global cancer mortality, often treated with
chemotherapeutic agents. However, conventional approaches such as oral or intravenous …

Comparison of the profiles of first-line PD-1/PD-L1 inhibitors for advanced NSCLC lacking driver gene mutations: a systematic review and Bayesian network meta …

F Wenfan, X Manman, S Xingyuan… - … in Chronic Disease, 2023 - journals.sagepub.com
Background: Numerous first-line immune checkpoint inhibitors (ICI) were developed for
patients with advanced non-small cell lung cancer (NSCLC) lacking driver gene mutations …