Zipping and unzipping: protein modifications regulating synaptonemal complex dynamics
J Gao, MP Colaiácovo - Trends in Genetics, 2018 - cell.com
The proteinaceous zipper-like structure known as the synaptonemal complex (SC), which
forms between pairs of homologous chromosomes during meiosis from yeast to humans …
forms between pairs of homologous chromosomes during meiosis from yeast to humans …
Phase separation during germline development
C So, S Cheng, M Schuh - Trends in cell biology, 2021 - cell.com
Phase separation has emerged as a new key principle of intracellular organization. Phase-
separated structures play diverse roles in various biological processes and pathogenesis of …
separated structures play diverse roles in various biological processes and pathogenesis of …
Superresolution expansion microscopy reveals the three-dimensional organization of the Drosophila synaptonemal complex
The synaptonemal complex (SC), a structure highly conserved from yeast to mammals,
assembles between homologous chromosomes and is essential for accurate chromosome …
assembles between homologous chromosomes and is essential for accurate chromosome …
[HTML][HTML] Dynamic architecture of DNA repair complexes and the synaptonemal complex at sites of meiotic recombination
A Woglar, AM Villeneuve - Cell, 2018 - cell.com
Meiotic double-strand breaks (DSBs) are generated and repaired in a highly regulated
manner to ensure formation of crossovers (COs) while also enabling efficient non-CO repair …
manner to ensure formation of crossovers (COs) while also enabling efficient non-CO repair …
Let's get physical–mechanisms of crossover interference
L von Diezmann, O Rog - Journal of cell science, 2021 - journals.biologists.com
The formation of crossovers between homologous chromosomes is key to sexual
reproduction. In most species, crossovers are spaced further apart than would be expected if …
reproduction. In most species, crossovers are spaced further apart than would be expected if …
Meiotic recombination modulates the structure and dynamics of the synaptonemal complex during C. elegans meiosis
D Pattabiraman, B Roelens, A Woglar… - PLoS …, 2017 - journals.plos.org
During meiotic prophase, a structure called the synaptonemal complex (SC) assembles at
the interface between aligned pairs of homologous chromosomes, and crossover …
the interface between aligned pairs of homologous chromosomes, and crossover …
Decoding sepsis-induced disseminated intravascular coagulation: a comprehensive review of existing and emerging therapies
A Unar, L Bertolino, F Patauner, R Gallo… - Journal of Clinical …, 2023 - mdpi.com
Disseminated intravascular coagulation (DIC) is a recurrent complication of sepsis. Since
DIC not only promotes organ dysfunction but also represents a strong prognostic factor, it is …
DIC not only promotes organ dysfunction but also represents a strong prognostic factor, it is …
A compartmentalized signaling network mediates crossover control in meiosis
L Zhang, S Köhler, R Rillo-Bohn, AF Dernburg - Elife, 2018 - elifesciences.org
During meiosis, each pair of homologous chromosomes typically undergoes at least one
crossover (crossover assurance), but these exchanges are strictly limited in number and …
crossover (crossover assurance), but these exchanges are strictly limited in number and …
Building the synaptonemal complex: Molecular interactions between the axis and the central region
The successful delivery of genetic material to gametes requires tightly regulated interactions
between the parental chromosomes. Central to this regulation is a conserved chromosomal …
between the parental chromosomes. Central to this regulation is a conserved chromosomal …
The kleisin subunit controls the function of C. elegans meiotic cohesins by determining the mode of DNA binding and differential regulation by SCC-2 and WAPL-1
M Castellano-Pozo, G Sioutas, C Barroso, JP Prince… - Elife, 2023 - elifesciences.org
The cohesin complex plays essential roles in chromosome segregation, 3D genome
organisation, and DNA damage repair through its ability to modify DNA topology. In higher …
organisation, and DNA damage repair through its ability to modify DNA topology. In higher …