NBD-based synthetic probes for sensing small molecules and proteins: design, sensing mechanisms and biological applications

C Jiang, H Huang, X Kang, L Yang, Z Xi… - Chemical Society …, 2021 - pubs.rsc.org
Compounds with a nitrobenzoxadiazole (NBD) skeleton exhibit prominent useful properties
including environmental sensitivity, high reactivity toward amines and biothiols (including …

Homocysteine and cardiovascular disease

H Refsum, PM Ueland, O Nygård… - Annual review of …, 1998 - annualreviews.org
An elevated level of total homocysteine (tHcy) in blood, denoted hyperhomocysteinemia, is
emerging as a prevalent and strong risk factor for atherosclerotic vascular disease in the …

[HTML][HTML] Reverse epidemiology of cardiovascular risk factors in maintenance dialysis patients

K Kalantar-Zadeh, G Block, MH Humphreys… - Kidney international, 2003 - Elsevier
Reverse epidemiology of cardiovascular risk factors in maintenance dialysis patients.
Conventional risk factors of cardiovascular disease and mortality in the general population …

Homocyst (e) ine, diet, and cardiovascular diseases: a statement for healthcare professionals from the Nutrition Committee, American Heart Association

MR Malinow, AG Bostom, RM Krauss - Circulation, 1999 - Am Heart Assoc
ported to have higher geometric mean fasting homocyst (e) ine levels than C/T
heterozygotes or C/C homozygotes when folate status was below the population median …

Increase in plasma homocysteine associated with parallel increases in plasma S-adenosylhomocysteine and lymphocyte DNA hypomethylation

P Yi, S Melnyk, M Pogribna, IP Pogribny… - Journal of Biological …, 2000 - ASBMB
S-Adenosylmethionine andS-adenosylhomocysteine (SAH), as the substrate and product of
essential cellular methyltransferase reactions, are important metabolic indicators of cellular …

ASPEN position paper: recommendations for changes in commercially available parenteral multivitamin and multi–trace element products

VW Vanek, P Borum, A Buchman… - Nutrition in Clinical …, 2012 - Wiley Online Library
The parenteral multivitamin preparations that are commercially available in the United
States (US) meet the requirements for most patients who receive parenteral nutrition (PN) …

[HTML][HTML] Kidney and eye diseases: common risk factors, etiological mechanisms, and pathways

CW Wong, TY Wong, CY Cheng, C Sabanayagam - Kidney international, 2014 - Elsevier
Chronic kidney disease is an emerging health problem worldwide. The eye shares striking
structural, developmental, and genetic pathways with the kidney, suggesting that kidney …

The treatment of hyperhomocysteinemia

BA Maron, J Loscalzo - Annual review of medicine, 2009 - annualreviews.org
The unique biochemical profile of homocysteine is characterized by chemical reactivity
supporting a wide range of molecular effects and by a tendency to promote oxidant stress …

[HTML][HTML] Homocysteine causes vascular endothelial dysfunction by disrupting endoplasmic reticulum redox homeostasis

X Wu, L Zhang, Y Miao, J Yang, X Wang, C Wang… - Redox biology, 2019 - Elsevier
Endothelial dysfunction induced by hyperhomocysteinemia (HHcy) plays a critical role in
vascular pathology. However, little is known about the role of endoplasmic reticulum (ER) …

Effect of homocysteine lowering on mortality and vascular disease in advanced chronic kidney disease and end-stage renal disease: a randomized controlled trial

RL Jamison, P Hartigan, JS Kaufman, DS Goldfarb… - Jama, 2007 - jamanetwork.com
ContextHigh plasma homocysteine levels are a risk factor for mortality and vascular disease
in observational studies of patients with chronic kidney disease. Folic acid and B vitamins …