NBD-based synthetic probes for sensing small molecules and proteins: design, sensing mechanisms and biological applications
Compounds with a nitrobenzoxadiazole (NBD) skeleton exhibit prominent useful properties
including environmental sensitivity, high reactivity toward amines and biothiols (including …
including environmental sensitivity, high reactivity toward amines and biothiols (including …
Homocysteine and cardiovascular disease
An elevated level of total homocysteine (tHcy) in blood, denoted hyperhomocysteinemia, is
emerging as a prevalent and strong risk factor for atherosclerotic vascular disease in the …
emerging as a prevalent and strong risk factor for atherosclerotic vascular disease in the …
[HTML][HTML] Reverse epidemiology of cardiovascular risk factors in maintenance dialysis patients
K Kalantar-Zadeh, G Block, MH Humphreys… - Kidney international, 2003 - Elsevier
Reverse epidemiology of cardiovascular risk factors in maintenance dialysis patients.
Conventional risk factors of cardiovascular disease and mortality in the general population …
Conventional risk factors of cardiovascular disease and mortality in the general population …
Homocyst (e) ine, diet, and cardiovascular diseases: a statement for healthcare professionals from the Nutrition Committee, American Heart Association
MR Malinow, AG Bostom, RM Krauss - Circulation, 1999 - Am Heart Assoc
ported to have higher geometric mean fasting homocyst (e) ine levels than C/T
heterozygotes or C/C homozygotes when folate status was below the population median …
heterozygotes or C/C homozygotes when folate status was below the population median …
Increase in plasma homocysteine associated with parallel increases in plasma S-adenosylhomocysteine and lymphocyte DNA hypomethylation
P Yi, S Melnyk, M Pogribna, IP Pogribny… - Journal of Biological …, 2000 - ASBMB
S-Adenosylmethionine andS-adenosylhomocysteine (SAH), as the substrate and product of
essential cellular methyltransferase reactions, are important metabolic indicators of cellular …
essential cellular methyltransferase reactions, are important metabolic indicators of cellular …
ASPEN position paper: recommendations for changes in commercially available parenteral multivitamin and multi–trace element products
VW Vanek, P Borum, A Buchman… - Nutrition in Clinical …, 2012 - Wiley Online Library
The parenteral multivitamin preparations that are commercially available in the United
States (US) meet the requirements for most patients who receive parenteral nutrition (PN) …
States (US) meet the requirements for most patients who receive parenteral nutrition (PN) …
[HTML][HTML] Kidney and eye diseases: common risk factors, etiological mechanisms, and pathways
Chronic kidney disease is an emerging health problem worldwide. The eye shares striking
structural, developmental, and genetic pathways with the kidney, suggesting that kidney …
structural, developmental, and genetic pathways with the kidney, suggesting that kidney …
The treatment of hyperhomocysteinemia
BA Maron, J Loscalzo - Annual review of medicine, 2009 - annualreviews.org
The unique biochemical profile of homocysteine is characterized by chemical reactivity
supporting a wide range of molecular effects and by a tendency to promote oxidant stress …
supporting a wide range of molecular effects and by a tendency to promote oxidant stress …
[HTML][HTML] Homocysteine causes vascular endothelial dysfunction by disrupting endoplasmic reticulum redox homeostasis
X Wu, L Zhang, Y Miao, J Yang, X Wang, C Wang… - Redox biology, 2019 - Elsevier
Endothelial dysfunction induced by hyperhomocysteinemia (HHcy) plays a critical role in
vascular pathology. However, little is known about the role of endoplasmic reticulum (ER) …
vascular pathology. However, little is known about the role of endoplasmic reticulum (ER) …
Effect of homocysteine lowering on mortality and vascular disease in advanced chronic kidney disease and end-stage renal disease: a randomized controlled trial
RL Jamison, P Hartigan, JS Kaufman, DS Goldfarb… - Jama, 2007 - jamanetwork.com
ContextHigh plasma homocysteine levels are a risk factor for mortality and vascular disease
in observational studies of patients with chronic kidney disease. Folic acid and B vitamins …
in observational studies of patients with chronic kidney disease. Folic acid and B vitamins …