Polyphenols: A first evidence in the synergism and bioactivities

S Mitra, AM Tareq, R Das, TB Emran… - Food Reviews …, 2023 - Taylor & Francis
Polyphenols are natural compounds and the most plentiful with synergistic properties
contributing to potential health benefits. This review describes the synergistic interactions of …

[HTML][HTML] Neuroprotective phytochemicals in experimental ischemic stroke: mechanisms and potential clinical applications

H Xu, E Wang, F Chen, J Xiao, M Wang - Oxidative medicine and …, 2021 - hindawi.com
Ischemic stroke is a challenging disease with high mortality and disability rates, causing a
great economic and social burden worldwide. During ischemic stroke, ionic imbalance and …

[HTML][HTML] Nanoformulations of herbal extracts in treatment of neurodegenerative disorders

SZ Moradi, S Momtaz, Z Bayrami… - … in bioengineering and …, 2020 - frontiersin.org
Nanotechnology is one of the methods that influenced human life in different ways and is a
substantial approach that assists to overcome the multiple limitations of various diseases …

Mitochondrial biogenesis as a therapeutic target for traumatic and neurodegenerative CNS diseases

EC Simmons, NE Scholpa, RG Schnellmann - Experimental neurology, 2020 - Elsevier
Central nervous system (CNS) diseases, both traumatic and neurodegenerative, are
characterized by impaired mitochondrial bioenergetics and often disturbed mitochondrial …

Flavonoids, the compounds with anti-inflammatory and immunomodulatory properties, as promising tools in multiple sclerosis (MS) therapy: a systematic review of …

P Bayat, M Farshchi, M Yousefian, M Mahmoudi… - International …, 2021 - Elsevier
Multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE), an animal
model of MS, are diseases resulting in neurological disabilities that are regarded as chronic …

[HTML][HTML] Lipocalin-2 may produce damaging effect after cerebral ischemia by inducing astrocytes classical activation

N Zhao, X Xu, Y Jiang, J Gao, F Wang, X Xu… - Journal of …, 2019 - Springer
Background Functions of astrocytes in the rehabilitation after ischemic stroke, especially
their impacts on inflammatory processes, remain controversial. This study uncovered two …

Microplastic-induced gut microbiota and serum metabolic disruption in Sprague-Dawley rats

N Zhao, M Zhao, H Jin - Environmental Pollution, 2023 - Elsevier
Toxic effects of exposure to microplastics (MPs) on living organisms and humans have
attracted global concern. However, most previous studies exposed animals to only one type …

[HTML][HTML] Verapamil inhibits mitochondria-induced reactive oxygen species and dependent apoptosis pathways in cerebral transient global ischemia/reperfusion

E Jangholi, ZN Sharifi, M Hoseinian… - … Medicine and Cellular …, 2020 - hindawi.com
The prefrontal cortex is the largest lobe of the brain and is consequently involved in stroke.
There is no comprehensive practical pharmacological strategy for ameliorating prefrontal …

Molecular mechanisms underlying the potential neuroprotective effects of Trifolium pratense and its phytoestrogen‐isoflavones in neurodegenerative disorders

AS Al‐Shami, AE Essawy… - Phytotherapy …, 2023 - Wiley Online Library
Neurodegenerative disorders are heterogeneous, debilitating, and incurable groups of brain
disorders that have common features including progressive degeneration of the structure …

Polyphenols and neurodegenerative diseases: Focus on neuronal regeneration

SZ Moradi, F Jalili, N Farhadian, T Joshi… - Critical reviews in …, 2022 - Taylor & Francis
Neurodegenerative diseases are questions that modern therapeutics can still not answer.
Great milestones have been achieved regarding liver, heart, skin, kidney and other types of …