Hepatitis B virus (HBV) is a non-cytopathic, hepatotropic virus with the potential to cause a
persistent infection, ultimately leading to cirrhosis and hepatocellular carcinoma. Over the …

This review article examines the structure and replication cycle of hepatitis B virus and
discusses the natural history of primary infection, the mechanisms of clearance of the virus …

Worldwide, some 240 million people have chronic hepatitis B virus (HBV), with the highest
rates of infection in Africa and Asia. Our understanding of the natural history of HBV infection …

Background & Aims Hepatitis B virus (HBV) has developed strategies to evade immune
responses. However, the mechanisms involved remain unclear. The NLRP3 inflammasome …

These guidelines have been written to assist physicians and other health care providers in
the recognition, diagnosis, and management of patients chronically infected with the …

Background & Aims: Hepatitis B virus (HBV) covalently closed circular DNA (cccDNA) is a
unique episomal replicative intermediate responsible for persistent infection of hepatocytes …

Chronic hepatitis B virus (HBV) infection has a complicated course. Three phases are
identified: an immune tolerant phase with high HBV DNA and normal alanine …

The adaptive immune response is thought to be responsible for viral clearance and disease
pathogenesis during hepatitis B virus infection. It is generally acknowledged that the …

Among the many viruses that are known to infect the human liver, hepatitis B virus (HBV)
and hepatitis C virus (HCV) are unique because of their prodigious capacity to cause …

Background & Aims: Treatment with adefovir dipivoxil for 48 weeks resulted in clinical
improvement in patients with hepatitis B e antigen (HBeAg)-negative chronic hepatitis B that …