[HTML][HTML] Mitochondrial dysfunction as a driver of cognitive impairment in Alzheimer's disease
Alzheimer's disease (AD) is the most frequent cause of age-related neurodegeneration and
cognitive impairment, and there are currently no broadly effective therapies. The underlying …
cognitive impairment, and there are currently no broadly effective therapies. The underlying …
[HTML][HTML] Glaucomatous optic neuropathy: Mitochondrial dynamics, dysfunction and protection in retinal ganglion cells
Glaucoma is a leading cause of irreversible blindness worldwide and is characterized by a
slow, progressive, and multifactorial degeneration of retinal ganglion cells (RGCs) and their …
slow, progressive, and multifactorial degeneration of retinal ganglion cells (RGCs) and their …
Kaempferol as a therapeutic agent in Alzheimer's disease: Evidence from preclinical studies
X Dong, S Zhou, J Nao - Ageing research reviews, 2023 - Elsevier
Background Alzheimer's disease (AD) is the most common type of dementia and seriously
affects human life and health. Kaempferol (KMP) is a common flavonoid, that is mainly …
affects human life and health. Kaempferol (KMP) is a common flavonoid, that is mainly …
[HTML][HTML] Comparative analysis of aducanumab, zagotenemab and pioglitazone as targeted treatment strategies for Alzheimer's disease
Alzheimer's disease (AD) is the leading cause of dementia that has remained a major
medical, sociocultural and economical challenge globally. Previously developed treatments …
medical, sociocultural and economical challenge globally. Previously developed treatments …
[HTML][HTML] Amyloid-beta and tau protein beyond Alzheimer's disease
The aggregation of amyloid-beta peptide and tau protein dysregulation are implicated to
play key roles in Alzheimer's disease pathogenesis and are considered the main …
play key roles in Alzheimer's disease pathogenesis and are considered the main …
[HTML][HTML] Key genes and biochemical networks in various brain regions affected in Alzheimer's disease
M Abyadeh, N Tofigh, S Hosseinian, M Hasan… - Cells, 2022 - mdpi.com
Alzheimer's disease (AD) is one of the most complicated progressive neurodegenerative
brain disorders, affecting millions of people around the world. Ageing remains one of the …
brain disorders, affecting millions of people around the world. Ageing remains one of the …
[HTML][HTML] TOMM40 Genetic Variants Cause Neuroinflammation in Alzheimer's Disease
YC Chen, SC Chang, YS Lee, WM Ho… - International Journal of …, 2023 - mdpi.com
Translocase of outer mitochondrial membrane 40 (TOMM40) is located in the outer
membrane of mitochondria. TOMM40 is essential for protein import into mitochondria …
membrane of mitochondria. TOMM40 is essential for protein import into mitochondria …
Proteomic study on the mechanism of arsenic neurotoxicity in the rat cerebral cortex and the protective mechanism of dictyophora polysaccharides against arsenic …
X Zhang, H Yang, Y Wang, J Zhang… - ACS Chemical …, 2023 - ACS Publications
Arsenic (As) is a toxic element, and long-term exposure to As can cause neurotoxicity. The
bioactive natural compound Dictyophora polysaccharide (DIP) from edible plants has been …
bioactive natural compound Dictyophora polysaccharide (DIP) from edible plants has been …
[HTML][HTML] Targeting the liver in dementia and cognitive impairment: Dietary macronutrients and diabetic therapeutics
Many people living with dementia and cognitive impairment have dysfunctional
mitochondrial and insulin-glucose metabolism resembling type 2 diabetes mellitus and old …
mitochondrial and insulin-glucose metabolism resembling type 2 diabetes mellitus and old …
[HTML][HTML] Apolipoprotein ε in brain and retinal neurodegenerative diseases
Alzheimer's disease (AD) is the most common form of dementia that remains incurable and
has become a major medical, social, and economic challenge worldwide. AD is …
has become a major medical, social, and economic challenge worldwide. AD is …