The notion that men are more variable than women has become embedded into scientific
thinking. For mental traits like personality, greater male variability has been partly attributed …

Simple Summary When male mice are kept in groups at animal facilities, aggressive
interactions between cage mates are not uncommon. Systematically reviewing previous …

Laboratory mice are typically housed in “shoebox” cages with limited opportunities to
engage in natural behaviour. Temporary access to environments with increased space and …

Compared to female mice raised in large, environmentally enriched (EE) cages, those from
“shoebox” non-enriched (NE) cages demonstrate more stereotypic behaviour (SB) and …

Biomedical research has made great strides in the past century leading to rapid advances in
human life expectancy, all derived from improved understanding, prevention, and treatment …

Natural products (NPs) often act as sources of CNS-active agents and provide inspiration for
the development of synthetic molecules that incorporate their best features. Vindeburnol …

Simple Summary The effect of housing on rodent well-being has received increasing
scrutiny in recent years in North America in an attempt to define adequate standards of …

Background Enrichment of home cages in laboratory experiments offers clear advantages,
but has been criticized in some respects. First, there is a lack of definition, which makes …

Abstract Space recommendations for mice made in the Guide for Care and Use of
Laboratory Animals have not changed since 1972, despite important improvements in …

Laboratory rodents raised in environmentally-enriched (EE) cages differ behaviourally and
cognitively from conventionally-housed (CH) animals. We hypothesised that mice can detect …