[HTML][HTML] Neurosteroids as regulators of neuroinflammation
Neuroinflammation is a physiological protective response in the context of infection and
injury. However, neuroinflammation, especially if chronic, may also drive …
injury. However, neuroinflammation, especially if chronic, may also drive …
Progesterone in the brain: hormone, neurosteroid and neuroprotectant
R Guennoun - International journal of molecular sciences, 2020 - mdpi.com
Progesterone has a broad spectrum of actions in the brain. Among these, the
neuroprotective effects are well documented. Progesterone neural effects are mediated by …
neuroprotective effects are well documented. Progesterone neural effects are mediated by …
Allopregnanolone: An overview on its synthesis and effects
S Diviccaro, L Cioffi, E Falvo, S Giatti… - Journal of …, 2022 - Wiley Online Library
Abstract Allopregnanolone, a 3α, 5α‐progesterone metabolite, acts as a potent allosteric
modulator of the γ‐aminobutyric acid type A receptor. In the present review, the synthesis of …
modulator of the γ‐aminobutyric acid type A receptor. In the present review, the synthesis of …
Nicotinic mitigation of neuroinflammation and oxidative stress after chronic sleep deprivation
R Xue, Y Wan, X Sun, X Zhang, W Gao… - Frontiers in …, 2019 - frontiersin.org
Sleep deprivation negatively influences all aspects of health. Oxidative stress and
inflammatory responses induced by sleep deprivation participate in its adverse effects but …
inflammatory responses induced by sleep deprivation participate in its adverse effects but …
Myrtenol ameliorates recognition memories' impairment and anxiety-like behaviors induced by asthma by mitigating hippocampal inflammation and oxidative stress in …
MA Bejeshk, AH Aminizadeh, E Jafari… - …, 2023 - karger.com
Introduction: Asthma is related to neurochemical alterations which affect brain functions and
lead to anxiety and cognitive dysfunctions. Myrtenol has sparked considerable interest due …
lead to anxiety and cognitive dysfunctions. Myrtenol has sparked considerable interest due …
Multiple sclerosis and neuroinflammation: the overview of current and prospective therapies
I Bjelobaba, D Savic, I Lavrnja - Current pharmaceutical design, 2017 - ingentaconnect.com
Persistent neuroinflammation is now recognized as a chief pathological component of
practically all neurodegenerative diseases. Neuroinflammation in the central nervous …
practically all neurodegenerative diseases. Neuroinflammation in the central nervous …
Progestogen-mediated neuroprotection in central nervous system disorders
TB Bassani, CS Bartolomeo, RB Oliveira… - …, 2023 - karger.com
Neuroactive steroids can be synthetic or endogenous molecules produced by neuronal and
glial cells and peripheral glands. Examples include estrogens, testosterone, progesterone …
glial cells and peripheral glands. Examples include estrogens, testosterone, progesterone …
[HTML][HTML] Disease stage-dependent changes in brain levels and neuroprotective effects of neuroactive steroids in Parkinson's disease
S Luchetti, P Liere, A Pianos, RWH Verwer… - Neurobiology of …, 2023 - Elsevier
Neuroactive steroids are known neuroprotective agents and neurotransmitter regulators. We
previously found that expression of the enzymes synthesizing 5α-dihydroprogesterone (5α …
previously found that expression of the enzymes synthesizing 5α-dihydroprogesterone (5α …
Microglial cell morphology and phagocytic activity are critically regulated by the neurosteroid allopregnanolone: A possible role in neuroprotection
V Jolivel, S Brun, F Binamé, J Benyounes, O Taleb… - Cells, 2021 - mdpi.com
Microglial cells are key players in neural pathogenesis and microglial function regulation
appears to be pivotal in controlling neuroinflammatory/neurological diseases. Here, we …
appears to be pivotal in controlling neuroinflammatory/neurological diseases. Here, we …
Apelin-13 ameliorates cognitive impairments in 6-hydroxydopamine-induced substantia nigra lesion in rats
Although Parkinson's disease (PD) is well known with its motor deficits, the patients often
suffer from cognitive dysfunction. Apelin, as the endogenous ligand of the APJ receptor, is …
suffer from cognitive dysfunction. Apelin, as the endogenous ligand of the APJ receptor, is …