Hippocampal learning, memory, and neurogenesis: Effects of sex and estrogens across the lifespan in adults

P Duarte-Guterman, S Yagi, C Chow, LAM Galea - Hormones and behavior, 2015 - Elsevier
This article is part of a Special Issue “Estradiol and Cognition”. There are sex differences in
hippocampus-dependent cognition and neurogenesis suggesting that sex hormones are …

Adult hippocampal neurogenesis: regulation and possible functional and clinical correlates

P Baptista, JP Andrade - Frontiers in neuroanatomy, 2018 - frontiersin.org
The formation of new neurons in the adult central nervous system (CNS) has been
recognized as one of the major findings in neuroanatomical research. The hippocampal …

Sex, hormones and neurogenesis in the hippocampus: hormonal modulation of neurogenesis and potential functional implications

LAM Galea, SR Wainwright, MM Roes… - Journal of …, 2013 - Wiley Online Library
The hippocampus is an area of the brain that undergoes dramatic plasticity in response to
experience and hormone exposure. The hippocampus retains the ability to produce new …

Hippocampal adult neurogenesis: Its regulation and potential role in spatial learning and memory

C Lieberwirth, Y Pan, Y Liu, Z Zhang, Z Wang - Brain research, 2016 - Elsevier
Adult neurogenesis, defined here as progenitor cell division generating functionally
integrated neurons in the adult brain, occurs within the hippocampus of numerous …

Histone deacetylase inhibition rescues structural and functional brain deficits in a mouse model of Kabuki syndrome

HT Bjornsson, JS Benjamin, L Zhang… - Science translational …, 2014 - science.org
Kabuki syndrome is caused by haploinsufficiency for either of two genes that promote the
opening of chromatin. If an imbalance between open and closed chromatin is central to the …

Sex differences in maturation and attrition of adult neurogenesis in the hippocampus

S Yagi, JEJ Splinter, D Tai, S Wong, Y Wen, LAM Galea - Eneuro, 2020 - eneuro.org
Sex differences exist in the regulation of adult neurogenesis in the hippocampus in
response to hormones and cognitive training. Here, we investigated the trajectory and …

Social instability stress in adolescent male rats alters hippocampal neurogenesis and produces deficits in spatial location memory in adulthood

CM McCormick, CM Thomas, CS Sheridan… - …, 2012 - Wiley Online Library
The ongoing development of the hippocampus in adolescence may be vulnerable to
stressors. The effects of social instability stress (SS) in adolescence (daily 1 h isolation and …

Sex differences in neurogenesis and activation of new neurons in response to spatial learning and memory

C Chow, JR Epp, SE Lieblich, CK Barha… - …, 2013 - Elsevier
Adult hippocampal neurogenesis is often associated with hippocampus-dependent learning
and memory. Throughout a new neuron's development, it is differentially sensitive to factors …

Could adult hippocampal neurogenesis be relevant for human behavior?

JS Snyder, HA Cameron - Behavioural brain research, 2012 - Elsevier
Although the function of adult neurogenesis is still unclear, tools for directly studying the
behavioral role of new hippocampal neurons now exist in rodents. Since similar studies are …

Hippocampus-dependent learning influences hippocampal neurogenesis

JR Epp, C Chow, LAM Galea - Frontiers in neuroscience, 2013 - frontiersin.org
The structure of the mammalian hippocampus continues to be modified throughout life by
continuous addition of neurons in the dentate gyrus. Although the existence of adult …