Epithelial structures are foundational for tissue organization in all metazoans. Sheets of
epithelial cells form lateral adhesive junctions and acquire apico-basal polarity …

Understanding the mechanisms driving tissue and organ formation requires knowledge
across scales. How do signaling pathways specify distinct tissue types? How does the …

Gamete development is a fundamental process that is highly conserved from early
eukaryotes to mammals. As germ cells develop, they must coordinate a dynamic series of …

Oscillating chemical reactions are common in biological systems and they also occur in
artificial non-biological systems. Generally, these reactions are subject to random …

A common path to the formation of complex 3D structures starts with an epithelial sheet that
is patterned by inductive cues that control the spatiotemporal activities of transcription …

The Drosophila eggshell constitutes a remarkable system for the study of epithelial
patterning, both experimentally and through computational modeling. Dorsal eggshell …

In living organisms, self-organised waves of signalling activity propagate spatiotemporal
information within tissues. During the development of the largest component of the visual …

The formation of three-dimensional structures from patterned epithelial sheets plays a key
role in tissue morphogenesis. An important class of morphogenetic mechanisms relies on …

Background information Epidermal growth factor receptor (EGFR) signalling is crucial for the
regulation of multiple developmental processes. Its function in relation to insect oogenesis …

Although it is widely appreciated that a typical developmental control gene is regulated by
multiple enhancers, coordination of enhancer activities remains poorly understood. We …