Chronic kidney disease (CKD) is estimated to affect 10–14% of global population. Kidney
fibrosis, characterized by excessive extracellular matrix deposition leading to scarring, is a …

Lupus nephritis (LN) is a major cause of morbidity and mortality among patients with
systemic lupus erythematosus (SLE). However, promising emerging biomarkers pave the …

Emerging urinary biomarkers continue to show promise in evaluating lupus nephritis (LN).
Here, we screen urine from active LN patients for 1129 proteins using an aptamer-based …

Systemic lupus erythematosus (SLE) is a multifactorial autoimmune disease which can affect
various tissues and organs, posing significant challenges for clinical diagnosis and …

Introduction The gold standard for diagnosis of active lupus nephritis (ALN), a kidney biopsy,
is invasive with attendant morbidity and cannot be serially repeated. Urinary ALCAM …

Objectives Serial kidney biopsy for repeat evaluation and monitoring of lupus nephritis (LN)
in childhood-onset Systemic Lupus Erythematosus (cSLE) remains challenging, thus non …

Lupus nephritis (LN), a major complication in individuals diagnosed with systemic lupus
erythematosus, substantially increases morbidity and mortality. Despite marked …

Background Lupus nephritis (LN) is one of the most severe complications of SLE patients.
We aim to validate urinary ALCAM as a biomarker in predicting renal disease histpathology …

Given the urgent need for non-invasive biomarkers of LN, we aim to identify novel urinary
biomarkers that facilitate diagnosis, assessment of disease activity and prediction of …

Introduction Systemic lupus erythematosus (SLE) is complex autoimmune disease with
heterogenous manifestations, unpredictable disease course and response to treatment. One …