Formulation and development of oral fast-dissolving films loaded with nanosuspension to augment paroxetine bioavailability: In vitro characterization, ex vivo …
AH Elshafeey, RM El-Dahmy - Pharmaceutics, 2021 - mdpi.com
Paroxetine (PX) is the most potent serotonin reuptake inhibitor utilized in depression and
anxiety treatment. It has drawbacks, such as having a very bitter taste, low water solubility …
anxiety treatment. It has drawbacks, such as having a very bitter taste, low water solubility …
Fabrication, optimization, and evaluation of paclitaxel and curcumin coloaded PLGA nanoparticles for improved antitumor activity
H Hu, Z Liao, M Xu, S Wan, Y Wu, W Zou, J Wu… - ACS …, 2022 - ACS Publications
Codelivery of chemotherapeutic drugs in nanoparticles can enhance the therapeutic effects
against tumors. However, their anticancer properties and physiochemical characteristics can …
against tumors. However, their anticancer properties and physiochemical characteristics can …
[HTML][HTML] pH-sensitive in situ gel of mirtazapine Invasomes for rectal drug delivery: Protruded bioavailability and anti-depressant efficacy
The present research emphasizes fabrication alongside the assessment of an innovative
nano-vesicular membranous system known as invasomes (NVMs) laden with Mirtazapine …
nano-vesicular membranous system known as invasomes (NVMs) laden with Mirtazapine …
[HTML][HTML] Formulation, optimization, in-vivo biodistribution studies and histopathological safety assessment of duloxetine HCl-loaded ultra-elastic nanovesicles for …
Duloxetine hydrochloride (DUL) is a BCS class-II antidepressant drug, acting via serotonin
and norepinephrine reuptake inhibition. Despite high oral absorption, DUL suffers limited …
and norepinephrine reuptake inhibition. Despite high oral absorption, DUL suffers limited …
Intranasal niosomal in situ gel as a novel strategy for improving citicoline efficacy and brain delivery in treatment of epilepsy: in vitro and ex vivo characterization and in …
The high hydrophilicity of citicoline and its rapid metabolism are the two main obstacles
hindering intact molecules from passing the blood-brain barrier. This study aimed to …
hindering intact molecules from passing the blood-brain barrier. This study aimed to …
Rethinking breast cancer chemoprevention: technological advantages and enhanced performance of a nanoethosomal-based hydrogel for topical administration of …
Herein, we developed an ethosomal hydrogel based on three types of ethosomes: simple,
mixed (surfactant-based micelles and lipid vesicles) or binary (comprising two type of …
mixed (surfactant-based micelles and lipid vesicles) or binary (comprising two type of …
Formulation of chitosan-coated brigatinib nanospanlastics: optimization, characterization, stability assessment and in-vitro cytotoxicity activity against H-1975 cell lines
RM Zaki, MM Alfadhel, SM Alshahrani, A Alsaqr… - Pharmaceuticals, 2022 - mdpi.com
The purpose of the current study was to develop Brigatinib (BGT)-loaded nanospanlastics
(BGT-loaded NSPs)(S1-S13) containing Span 60 with different edge activators (Tween 80 …
(BGT-loaded NSPs)(S1-S13) containing Span 60 with different edge activators (Tween 80 …
Implementing losartan potassium-laden pegylated nanocubic vesicles as a novel nanoplatform to alleviate cisplatin-induced nephrotoxicity via blocking apoptosis and …
Aims Losartan potassium-laden pegylated nanocubic vesicles (LP-NCVs-PEG) have an
intriguing kidney-targeted nanoplatform for acute renal injury via blocking apoptosis and …
intriguing kidney-targeted nanoplatform for acute renal injury via blocking apoptosis and …
Intratracheally Inhalable Nifedipine-Loaded Chitosan-PLGA Nanocomposites as a Promising Nanoplatform for Lung Targeting: Snowballed Protection via Regulation …
Pulmonary fibrosis is a serious ailment that may progress to lung remodeling and
demolition, where the key participants in its incidence are fibroblasts responding to growth …
demolition, where the key participants in its incidence are fibroblasts responding to growth …
Tunable polymeric mixed micellar nanoassemblies of lutrol F127/Gelucire 44/14 for oral delivery of praziquantel: A promising nanovector against hymenolepis nana in …
Hymenolepiasis represents a parasitic infection of common prevalence in pediatrics with
intimidating impacts, particularly amongst immunocompromised patients. The present work …
intimidating impacts, particularly amongst immunocompromised patients. The present work …