Mechanisms underlying mechanical overload-induced skeletal muscle hypertrophy have
been extensively researched since the landmark report by Morpurgo (1897) of “work …

Societies are progressively aging, with the oldest old (ie., those aged> 80–85 years) being
the most rapidly expanding population segment. However, advanced aging comes at a …

Background Older adults experience considerable muscle and bone loss that are closely
interconnected. The efficacy of progressive resistance training programs to concurrently …

Skeletal muscle plays a pivotal role in the maintenance of physical and metabolic health
and, critically, mobility. Accordingly, strategies focused on increasing the quality and quantity …

Background Reductions in muscle size and strength occur with aging. These changes can
be mitigated by participation in resistance training. At present, it is unknown if sex …

Age-associated chronic basal inflammation compromises muscle mass and adaptability, but
exercise training may exert an anti-inflammatory effect. This investigation assessed basal …

The neuromuscular junction (NMJ) is a specialized synapse that bridges the motor neuron
and the skeletal muscle fiber and is crucial for conversion of electrical impulses originating …

Sarcopenia is an age‐related progressive muscle disease characterized by loss of muscle
mass, muscle strength and physical performance with high prevalence in chronic kidney …

For centuries, regular exercise has been acknowledged as a potent stimulus to promote,
maintain, and restore healthy functioning of nearly every physiological system of the human …

Murine exercise models can provide information on factors that influence muscle
adaptability with aging, but few translatable solutions exist. Progressive weighted wheel …