Lipid droplets and lipid mediators in viral infection and immunity
Lipid droplets (LDs) contribute to key pathways important for the physiology and
pathophysiology of cells. In a homeostatic view, LDs regulate the storage of neutral lipids …
pathophysiology of cells. In a homeostatic view, LDs regulate the storage of neutral lipids …
Defining virulence genes in the dimorphic fungi
CA Rappleye, WE Goldman - Annu. Rev. Microbiol., 2006 - annualreviews.org
Most dimorphic fungal pathogens cause respiratory disease in mammals and must therefore
possess virulence mechanisms to combat and overcome host pulmonary defenses. Over the …
possess virulence mechanisms to combat and overcome host pulmonary defenses. Over the …
RNA interference in Histoplasma capsulatum demonstrates a role for α‐(1,3)‐glucan in virulence
CA Rappleye, JT Engle, WE Goldman - Molecular microbiology, 2004 - Wiley Online Library
Histoplasma capsulatum is a fungal pathogen that causes respiratory and systemic disease
by proliferating within macrophages. While much is known about histoplasmosis, only a …
by proliferating within macrophages. While much is known about histoplasmosis, only a …
Anti-inflammatory effects of Lafoensia pacari and ellagic acid in a murine model of asthma
AP Rogerio, C Fontanari, É Borducchi, AC Keller… - European journal of …, 2008 - Elsevier
We have shown that the ethanolic extract of Lafoensia pacari inhibits eosinophilic
inflammation induced by Toxocara canis infection, and that ellagic acid is the secondary …
inflammation induced by Toxocara canis infection, and that ellagic acid is the secondary …
Neutrophil-Mediated Immunopathology and Matrix Metalloproteinases in Central Nervous System–Tuberculosis
Tuberculosis (TB) remains one of the leading infectious killers in the world, infecting
approximately a quarter of the world's population with the causative organism …
approximately a quarter of the world's population with the causative organism …
[HTML][HTML] Eicosanoid pathway on host resistance and inflammation during Mycobacterium tuberculosis infection is comprised by LTB4 reduction but not PGE2 …
The functions of eicosanoids, a family of potent biologically active lipid mediators, are not
restricted to inflammatory responses and they also act as mediators of the pathogenesis …
restricted to inflammatory responses and they also act as mediators of the pathogenesis …
Blockade of endogenous leukotrienes exacerbates pulmonary histoplasmosis
AI Medeiros, A Sá-Nunes, EG Soares… - Infection and …, 2004 - Am Soc Microbiol
Leukotrienes are classical mediators of inflammatory response. New aspects of leukotriene
function have recently been described. We examine here the previously unreported role that …
function have recently been described. We examine here the previously unreported role that …
Anti-inflammatory, analgesic and anti-oedematous effects of Lafoensia pacari extract and ellagic acid
AP Rogerio, C Fontanari, MCC Melo… - Journal of Pharmacy …, 2006 - academic.oup.com
Abstract Lafoensia pacari St. Hil.(Lythraceae) is used in traditional medicine to treat
inflammation. Previously, we demonstrated the anti-inflammatory effect that the ethanolic …
inflammation. Previously, we demonstrated the anti-inflammatory effect that the ethanolic …
Targeting neutrophils for host-directed therapy to treat tuberculosis
T Dallenga, L Linnemann, B Paudyal, U Repnik… - International Journal of …, 2018 - Elsevier
M. tuberculosis is one of the prime killers from infectious diseases worldwide. Infections with
multidrug-resistant variants counting for almost half a million new cases per year are steadily …
multidrug-resistant variants counting for almost half a million new cases per year are steadily …
COVID-19: Integrating the complexity of systemic and pulmonary immunopathology to identify biomarkers for different outcomes
In the last few months, the coronavirus disease 2019 (COVID-19) pandemic has affected
millions of people worldwide and has provoked an exceptional effort from the scientific …
millions of people worldwide and has provoked an exceptional effort from the scientific …