[HTML][HTML] Mesenchymal stem cell-derived extracellular vesicles for immunomodulation and regeneration: a next generation therapeutic tool?
M Kou, L Huang, J Yang, Z Chiang, S Chen, J Liu… - Cell death & …, 2022 - nature.com
Mesenchymal stem cells (MSCs) can be widely isolated from various tissues including bone
marrow, umbilical cord, and adipose tissue, with the potential for self-renewal and …
marrow, umbilical cord, and adipose tissue, with the potential for self-renewal and …
Growth differentiation factor 15 in adverse cardiac remodelling: from biomarker to causal player
M Wesseling, JHC de Poel, SCA de Jager - ESC Heart Failure, 2020 - Wiley Online Library
Heart failure is a growing health issue as a negative consequence of improved survival
upon myocardial infarction, unhealthy lifestyle, and the ageing of our population. The large …
upon myocardial infarction, unhealthy lifestyle, and the ageing of our population. The large …
[HTML][HTML] Human Mesenchymal stem cells program macrophage plasticity by altering their metabolic status via a PGE2-dependent mechanism
AB Vasandan, S Jahnavi, C Shashank, P Prasad… - Scientific reports, 2016 - nature.com
Mesenchymal stem cells (MSCs) are speculated to act at macrophage-injury interfaces to
mediate efficient repair. To explore this facet in-depth this study evaluates the influence of …
mediate efficient repair. To explore this facet in-depth this study evaluates the influence of …
[HTML][HTML] Mitochondrial transfer of mesenchymal stem cells effectively protects corneal epithelial cells from mitochondrial damage
Recent studies have demonstrated that mesenchymal stem cells (MSCs) can donate
mitochondria to airway epithelial cells and rescue mitochondrial damage in lung injury. We …
mitochondria to airway epithelial cells and rescue mitochondrial damage in lung injury. We …
[PDF][PDF] iPSC-MSCs with high intrinsic MIRO1 and sensitivity to TNF-α yield efficacious mitochondrial transfer to rescue anthracycline-induced cardiomyopathy
Mesenchymal stem cells (MSCs) can donate mitochondria and rescue anthracycline-
induced cardiomyocyte (CM) damage, although the underlying mechanisms remain elusive …
induced cardiomyocyte (CM) damage, although the underlying mechanisms remain elusive …
[HTML][HTML] Autophagy promotes MSC-mediated vascularization in cutaneous wound healing via regulation of VEGF secretion
Y An, WJ Liu, P Xue, Y Ma, LQ Zhang, B Zhu, M Qi… - Cell death & …, 2018 - nature.com
Vascularization deficiency caused a lot of diseases, such as diabetes ulcer and myocardial
infarction. Mesenchymal stem cells (MSCs), with the self-renewal and multipotent …
infarction. Mesenchymal stem cells (MSCs), with the self-renewal and multipotent …
Hepatoprotective effect of exosomes from human-induced pluripotent stem cell–derived mesenchymal stromal cells against hepatic ischemia-reperfusion injury in rats
K Nong, W Wang, X Niu, B Hu, C Ma, Y Bai, B Wu… - Cytotherapy, 2016 - Elsevier
Background This study aimed to evaluate the effect of exosomes produced by human-
induced pluripotent stem cell–derived mesenchymal stromal cells (hiPSC-MSCs-Exo) on …
induced pluripotent stem cell–derived mesenchymal stromal cells (hiPSC-MSCs-Exo) on …
Exosomes from mesenchymal stem cells overexpressing MIF enhance myocardial repair
Accumulating evidence has shown that mesenchymal stem cell (MSC)‐derived exosomes
(exo) mediate cardiac repair following myocardial infarction (MI). Macrophage migration …
(exo) mediate cardiac repair following myocardial infarction (MI). Macrophage migration …
miR‐155‐5p inhibition rejuvenates aged mesenchymal stem cells and enhances cardioprotection following infarction
Y Hong, H He, G Jiang, H Zhang, W Tao, Y Ding… - Aging cell, 2020 - Wiley Online Library
Aging impairs the functions of human mesenchymal stem cells (MSCs), thereby severely
reducing their beneficial effects on myocardial infarction (MI). MicroRNAs (miRNAs) play …
reducing their beneficial effects on myocardial infarction (MI). MicroRNAs (miRNAs) play …
[HTML][HTML] Extracellular vesicles derived from human ES-MSCs protect retinal ganglion cells and preserve retinal function in a rodent model of optic nerve injury
SZ Seyedrazizadeh, S Poosti, A Nazari… - Stem cell research & …, 2020 - Springer
Background Retinal and/or optic nerve injury is one of the leading causes of blindness due
to retinal ganglion cell (RGC) degeneration. There have been extensive efforts to suppress …
to retinal ganglion cell (RGC) degeneration. There have been extensive efforts to suppress …