While low levels of unesterified long chain fatty acids (LCFAs) are normal metabolic
intermediates of dietary and endogenous fat, LCFAs are also potent regulators of key …

Since its discovery three decades ago, sterol carrier protein-2 (SCP-2) has remained a
fascinating protein whose physiological function in lipid metabolism remains an enigma. Its …

Publisher Summary This chapter focuses on the techniques used for ecdysteroid analysis
and the biosynthesis and metabolism of these hormones. Ecdysteroids could be defined …

The steroidogenic acute regulatory protein (StAR) mediates the rate-limiting step of
steroidogenesis, delivery of cholesterol to the inner mitochondrial membrane. However, the …

Cellular cholesterol homeostasis is a balance of influx, catabolism and synthesis, and efflux.
Unlike vascular lipoprotein cholesterol transport, intracellular cholesterol trafficking is only …

Sterol carrier protein-2 (SCP-2) was independently discovered as a soluble protein that
binds and transfers cholesterol as well as phospholipids (nonspecific lipid transfer protein …

Non-alcoholic fatty liver disease (NAFLD) is considered as the most common chronic liver
disease and has become a rapidly global public health problem. Sterol carrier protein 2 …

The multiple actions of sterol carrier protein-2 (SCP-2) in intracellular lipid circulation and
metabolism originate from its gene and protein structure. The SCP-x/pro-SCP-2 gene is a …

Yellow fever mosquito sterol carrier protein (SCP-2) is known to bind to cholesterol. We
report here the three-dimensional structure of the complex of SCP-2 from Aedes aegypti with …

Cholesterol itself has very few structural/chemical features suitable for real-time imaging in
living cells. Thus, the advent of dehydroergosterol [ergosta-5, 7, 9 (11), 22-tetraen-3β-ol …