The cytoskeleton in phagocytosis and macropinocytosis
Cells of the innate immune system, notably macrophages, neutrophils and dendritic cells,
perform essential antimicrobial and homeostatic functions. These functions rely on the …
perform essential antimicrobial and homeostatic functions. These functions rely on the …
Endocytosis of abiotic nanomaterials and nanobiovectors: Inhibition of membrane trafficking
P Makvandi, M Chen, R Sartorius, A Zarrabi… - Nano Today, 2021 - Elsevier
Humans are exposed to nanoscopical nanobiovectors (eg coronavirus SARS-CoV-2) as
well as abiotic metal/carbon-based nanomaterials that enter cells serendipitously or …
well as abiotic metal/carbon-based nanomaterials that enter cells serendipitously or …
[HTML][HTML] Pay attention to membrane tension: Mechanobiology of the cell surface
E Sitarska, A Diz-Muñoz - Current opinion in cell biology, 2020 - Elsevier
The cell surface is a mechanobiological unit that encompasses the plasma membrane, its
interacting proteins, and the complex underlying cytoskeleton. Recently, attention has been …
interacting proteins, and the complex underlying cytoskeleton. Recently, attention has been …
Physical constraints and forces involved in phagocytosis
V Jaumouillé, CM Waterman - Frontiers in immunology, 2020 - frontiersin.org
Phagocytosis is a specialized process that enables cellular ingestion and clearance of
microbes, dead cells and tissue debris that are too large for other endocytic routes. As such …
microbes, dead cells and tissue debris that are too large for other endocytic routes. As such …
Spatiotemporal dynamics of membrane surface charge regulates cell polarity and migration
During cell migration and polarization, numerous signal transduction and cytoskeletal
components self-organize to generate localized protrusions. Although biochemical and …
components self-organize to generate localized protrusions. Although biochemical and …
Macrophage mitochondrial fission improves cancer cell phagocytosis induced by therapeutic antibodies and is impaired by glutamine competition
J Li, Y Ye, Z Liu, G Zhang, H Dai, J Li, B Zhou, Y Li… - Nature cancer, 2022 - nature.com
Phagocytosis is required for the optimal efficacy of many approved and promising
therapeutic antibodies for various malignancies. However, the factors that determine the …
therapeutic antibodies for various malignancies. However, the factors that determine the …
Dynamic plasma membrane organization: a complex symphony
S van Deventer, AB Arp, AB van Spriel - Trends in Cell Biology, 2021 - cell.com
Membrane protein organization is essential for proper cellular functioning and the result of a
dynamic exchange between protein monomers, nanoscale protein clusters, and microscale …
dynamic exchange between protein monomers, nanoscale protein clusters, and microscale …
Phagocytic 'teeth'and myosin-II 'jaw'power target constriction during phagocytosis
Phagocytosis requires rapid actin reorganization and spatially controlled force generation to
ingest targets ranging from pathogens to apoptotic cells. How actomyosin activity directs …
ingest targets ranging from pathogens to apoptotic cells. How actomyosin activity directs …
A theoretical model of efficient phagocytosis driven by curved membrane proteins and active cytoskeleton forces
Phagocytosis is the process of engulfment and internalization of comparatively large
particles by cells, and plays a central role in the functioning of our immune system. We study …
particles by cells, and plays a central role in the functioning of our immune system. We study …
Local translation in microglial processes is required for efficient phagocytosis
MJ Vasek, SM Mueller, SB Fass… - Nature …, 2023 - nature.com
Neurons, astrocytes and oligodendrocytes locally regulate protein translation within distal
processes. Here, we tested whether there is regulated local translation within peripheral …
processes. Here, we tested whether there is regulated local translation within peripheral …