Interleukin-6 (IL-6) is an acknowledged inflammatory cytokine with a pleiotropic action,
mediating innate and adaptive immunity and multiple physiological processes, including …

For a successful pregnancy to occur, a predecidualized receptive endometrium must be
invaded by placental differentiated cells (extravillous trophoblast cells (EVTs)) and, at the …

Abstract Background Enhancer RNAs (eRNAs) are a group of lncRNAs transcribed from
enhancers, whose regulatory effects on gene expression are an emerging area of interest …

Preclinical studies reveal maternal exercise as a promising intervention to reduce the
transmission of multigenerational metabolic dysfunction caused by maternal obesity. The …

The blastocyst expresses paternally derived alloantigens and induces inflammation during
implantation. However, it is necessary for the onset of pregnancy. An abnormal response …

Oxidative stress is the result of an imbalance between the formation of reactive oxygen
species (ROS) and the levels of enzymatic and non-enzymatic antioxidants. The assessment …

Precise extravillous trophoblast (EVT) invasion is crucial for successful placentation and
pregnancy. This review focuses on elucidating the mechanisms that promote heightened …

APOBEC-induced mutations occur in 50% of sequenced human tumors, with APOBEC3A
(A3A) being a major contributor to mutagenesis in breast cancer cells. The mechanisms that …

The members of human miR-17-92 cluster are implicated in several cancers and are known
to increase cancer cells invasiveness. The present study reports reduced expression of miR …

Objective Vascular endothelial growth factor (VEGF) plays a critical role in regulating
trophoblast cell invasion and proliferation, involved in a variety of pregnancy complications …