Articular cartilage has a low self-repair capacity due to the lack of vessels and nerves. In
recent times, nanofiber scaffolds have been widely used for this purpose. The optimum …

Successful regeneration of large segmental bone defects remains a major challenge in
clinical orthopedics, thus it is of important significance to fabricate a suitable alternative …

Articular hyaline cartilage is extensively hydrated, but it is neither innervated nor
vascularized, and its low cell density allows only extremely limited self-renewal. Most clinical …

The development of biomaterials, stem cells and bioactive factors has led to cartilage tissue
engineering becoming a promising tactic to repair cartilage defects. Various polymer three …

Bone tissue engineering is a highly interdisciplinary field that seeks to tackle the most
challenging bone-related clinical issues. The major components of bone tissue engineering …

In the US, 30% of adults suffer joint pain, most commonly in the knee, which severely limits
mobility and is often attributed to injury of cartilage and underlying bone in the joint. Current …

To repair complexly shaped tissue defects, an injectable cell carrier is desirable to achieve
an accurate fit and to minimize surgical intervention. However, the injectable carriers …

The development of a new family of implantable bioinspired materials is a focal point of
bone tissue engineering. Implant surfaces that better mimic the natural bone extracellular …

Tissue-engineered small-diameter vascular grafts are needed for patients requiring
replacement of their injured coronary and below-the-knee vessels. Understanding the …

Chitosan acetate nano-fibers were fabricated via a solid–liquid phase separation technique.
The chitosan acetate structure was influenced by phase separation temperature, chitosan …