Among diseases whose cure is still far from being discovered, Alzheimer's disease (AD) has
been recognized as a crucial medical and social problem. A major issue in AD research is …

Heat shock proteins (Hsps) represent the most evolutionarily ancient, conserved, and
universal system for protecting cells and the whole body from various types of stress. Among …

Protein misfolding causes aggregation and build-up in a variety of brain diseases. There are
numeral molecules that are linked with the protein homeostasis mechanism. Molecular …

Our review seeks to elucidate the current state-of-the-art in studies of 70-kilodalton-weighed
heat shock proteins (Hsp70) in neurodegenerative diseases (NDs). The family has already …

The lack of effective therapies that slow the progression of Alzheimer's disease (AD) and
related tauopathies highlights the need for a more comprehensive understanding of the …

The development of oxidative stress inevitably causes damage to cell proteins in need of
timely refolding. The synthesis of the proteins of the heat-shock group is the most ancient …

Alzheimer's disease (AD) is a neurodegenerative disease that inevitably results in dementia
and death. Currently, there are no pathogenetically grounded methods for the prevention …

Neuroinflammation is implicated in central nervous system (CNS) diseases, but the
molecular mechanisms involved are poorly understood. Progress may be accelerated by …

In humans, heat shock protein 70 is a key component of the machinery that protects
neuronal cells from various stress conditions and whose production significantly declines …

Cadmium, a neurotoxic environmental compound, produces cognitive disorders, although
the mechanism remains unknown. Cadmium induces a more pronounced cell death on …