Wnt/beta-catenin signaling confers ferroptosis resistance by targeting GPX4 in gastric cancer

Y Wang, L Zheng, W Shang, Z Yang, T Li… - Cell Death & …, 2022 - nature.com
The development of chemotherapy resistance is the most vital obstacle to clinical efficacy in
gastric cancer (GC). The dysregulation of the Wnt/beta-catenin signaling pathway is critically …

Metabolic reprogramming in colorectal cancer: regulatory networks and therapy

J Zhang, S Zou, L Fang - Cell & Bioscience, 2023 - Springer
With high prevalence and mortality, together with metabolic reprogramming, colorectal
cancer is a leading cause of cancer-related death. Metabolic reprogramming gives tumors …

WNT/β‐catenin pathway is a key regulator of cardiac function and energetic metabolism

VV Balatskyi, A Sowka, P Dobrzyn… - Acta …, 2023 - Wiley Online Library
The WNT/β‐catenin pathway is a master regulator of cardiac development and growth, and
its activity is low in healthy adult hearts. However, even this low activity is essential for …

Circular RNA circRNF13 inhibits proliferation and metastasis of nasopharyngeal carcinoma via SUMO2

Y Mo, Y Wang, S Zhang, F Xiong, Q Yan, X Jiang… - Molecular cancer, 2021 - Springer
Abstract Background Circular RNAs (circRNAs) are widely expressed in human cells and
are closely associated with cancer development. However, they have rarely been …

Long non-coding RNA LINC00174 promotes glycolysis and tumor progression by regulating miR-152-3p/SLC2A1 axis in glioma

J Shi, Y Zhang, B Qin, Y Wang, X Zhu - Journal of Experimental & Clinical …, 2019 - Springer
Background Long non-coding RNA plays a crucial role in the occurrence and progression of
glioma. We aimed to explore the function of LINC00174 in cell proliferation, apoptosis …

The roles of zinc finger proteins in colorectal cancer

AS Iyer, MR Shaik, JP Raufman, G Xie - International journal of molecular …, 2023 - mdpi.com
Despite colorectal cancer remaining a leading worldwide cause of cancer-related death,
there remains a paucity of effective treatments for advanced disease. The molecular …

Resistance to FGFR1-targeted therapy leads to autophagy via TAK1/AMPK activation in gastric cancer

R Peng, Y Chen, L Wei, G Li, D Feng, S Liu, R Jiang… - Gastric Cancer, 2020 - Springer
Background Fibroblast growth factor receptor 1 (FGFR1) is frequently dysregulated in
various tumors. FGFR inhibitors have shown promising therapeutic value in several …

The expression of SERPINE1 in colon cancer and its regulatory network and prognostic value

Y Wang, J Wang, J Gao, M Ding, H Li - BMC gastroenterology, 2023 - Springer
Abstract Background Serpin Peptidase Inhibitor 1 (SERPINE1) promotes cancer progression
by making it easier for cancer cells to spread to surrounding normal tissue. We expect to …

LncRNA TUG1 competitively binds to miR‐340 to accelerate myocardial ischemia‐reperfusion injury

X Wu, Y Liu, S Mo, W Wei, Z Ye, Q Su - The FASEB Journal, 2021 - Wiley Online Library
The aberrant expression of long noncoding RNA (lncRNA) taurine‐upregulated gene 1
(TUG1) has been previously associated with myocardial ischemia‐reperfusion injury (MIRI) …

Zic1 suppresses gastric cancer metastasis by regulating Wnt/β‐catenin signaling and epithelial‐mesenchymal transition

Q Ge, Y Hu, J He, F Chen, L Wu, X Tu, Y Qi… - The FASEB …, 2020 - Wiley Online Library
Gastric cancer (GC) patients with metastasis had limited treatment options and dismal
outcome. We have previously reported the aberrant expression of Zic family member 1 (Zic1) …